Peak expiratory flow (PEF) and plasma concentrations of platelet factor 4 and beta thromboglobulin were measured before and after exercise in nine asthmatic patients and 12 non-asthmatic volunteers. Exercise was preceded by administration in random order of either placebo, salbutamol 200 micrograms, or sodium cromoglycate 2 mg from a pressurised inhaler. In control subjects there were minimal c...

Panel studies have found 1-3% increases in reports of acute respiratory symptoms associated with each 10 microg x m(-3) increase in ambient concentrations of particles with a 50% cut-off aerodynamic diameter of 10 microm (PM10). Statistically significant decrements in population mean peak expiratory flow (PEF) have also been observed but their magnitude is only about 0.1% for the same exposure....

STUDY OBJECTIVE To determine if peak expiratory flow (PEF) is higher using incorrect technique versus correct technique with five marketed peak flowmeters. DESIGN Randomized, nonblinded study. SETTING University pulmonary medicine clinic. PATIENTS Twenty adults with clinically stable asthma. INTERVENTIONS After inhaling 2 puffs of albuterol via a valved aerosol holding chamber (Aerocham...

Methods and results We compared survival in patients with HF-PEF with that in patients with HF-REF in a meta-analysis using individual patient data. Preserved EF was defined as an EF ≥ 50%. The 31 studies included 41 972 patients: 10 347 with HF-PEF and 31 625 with HF-REF. Compared with patients with HF-REF, those with HF-PEF were older (mean age 71 vs. 66 years), were more often women (50 vs. ...

STUDY OBJECTIVES To evaluate features of the peak expiratory flow (PEF) test protocol, and to characterize patterns of reproducibility in multiple PEF measurements. DESIGN Cross-sectional study. SETTING University population. PARTICIPANTS Two hundred twenty-three healthy adults. INTERVENTIONS Participants recorded five PEF measurements in each of five sessions per day for 1 week. MEAS...

Measuring resource efficiency can be achieved using different methods, of which primary energy demand is commonly used. The primary energy factor (PEF) is a figure describing how much energy from primary resources is being used per unit of energy delivered. The PEF for nuclear power is typically 3, which refers to thermal energy released from fission in relation to electricity generated. Fuel l...

Lysophosphatidylcholine (LPC) plays an important role in atherosclerosis through initiation of endothelial inflammation response. Paeoniflorin (PEF), isolated from the dry root of Paeonia, has been reported to exert an anti-inflammatory effect, but the exact mechanism is not fully understood. The aim of this study was to investigate the inhibitory effects of PEF on LPC-induced inflammatory fact...

In this study, the use of pulsed electric field (PEF) for extraction polyphenols from mature Elaeagnus pungens ‘Limelight’ leaves is discussed. Optimization main parameters that affect process was carried out. More specifically, composition solvent (ethanol, water, and mixtures two at a 25% v/v step gradient) PEF-related (i.e., pulse duration, period, intensity) optimized. The obtained extracts...

Polypeptide chain elongation factor l a (EF-la) is an eukaryotic counterpart of E. coli EF-Tu which promotes the GTP-dependent binding of an aminoacyl-tRNA to ribosomes. EF-la is one of the most abundant proteins in eukaryotic cells, and expressed in almost all kinds of mammalian cells. Recently, we have isolated human chromosomal gene coding for EF-la, and shown that the promoter of EF-la chro...