objective: perovskia abrotanoides karel, belongs to the family lamiaceae and grows wild alongside the mountainous roads inarid and cold climate of northern iran. the anti-tumor activity of p. abrotanoides root extract has been shown previously. this study was designed to examine in vitro anti-proliferative and pro-apoptotic effects of flower extract of p. abrotanoides on mcf-7 and hela cell lin...

objective(s):hypoxia induces cellular oxidative stress that is associated with neurodegenerative diseases. here, the protective effects of ferulic acid (fa) on hypoxia-induced neurotoxicity in pc12 cells were evaluated. materials and methods:we investigated the effect of fa on pc12 cells subjected to hypoxia stress, in vitro. results:fa increased cell viability, prevented membrane damage (ldh r...

background: we aimed to assess the effects of anise on quality of life (qol) of patients with functional dyspepsia (fd) in a double-blind randomized clinical trial. materials and methods: of 180 patients attending the gastroenterology clinic, 107 ones with the diagnosis of postprandial distress syndrome according to rome iii criteria were enrolled. they were randomized into two groups, anise an...

in this study, a simple and low-cost method was developed for extraction and pre-concentration of brilliant blue(bb) and tropaeolin o(to) in food samples using cloud point extraction (cpe) prior to spectrophotometric determination. the effects of main factors such as ph, surfactant and salt concentrations, incubation time and temperature on the cloud point extraction of both dyes were investiga...

background: obesity associated with type 2 diabetes, and hypertension increased mortality and morbidity. glutamate decarboxylase 2 (gad2) gene is associated with obesity and it regulate food intake and insulin level. we investigated the association of gad-2gene −243a>g (rs2236418) and +61450c>a (rs992990) polymorphisms with obesity and related phenotypes. methods: insulin, glucose and lipid lev...

normal 0 false false false en-us x-none ar-sa background: alzheimer's disease (ad) is a progressive neurodegenerative disease in which endothelial cell (ec) can be affected. in brain, functional changes in ecs contribute to reductions in resting blood flow. furthermore, angiotensin-converting enzyme inhibitors (ace-i) have beneficial effects on endothelial dysfunction. this is the first study t...

background: the association between lipid peroxidation biomarkers and adipocytokines is hypothesized in preeclampsia but little is known about it. objective: the present study was undertaken to determine the association of lipid peroxidation biomarkers measured by the levels of 8-isoprostane and malondialdehyde with adipocytokines leptin and adiponectin in maternal serum of preeclamptic women. ...

for the first time b-podands have been studied as an efficient and powerful catalysts in the ring opening of epoxides with azide anion in water. the reaction afforded the corresponding 1,2-azidoalcohols with high regioselectivity under mild reaction conditions and in a highly atom economic fashion.

fine particles silicoaluminophosphate-34 were synthesized by hydrothermal sol-gel method. the effect of crystallization time, as one of the important synthesis factors on particle size and crystallinity, kinetic and equilibrium adsorption, and selectivity of co2 / ch4 has been studied in this work. the adsorption isotherms are obtained at moderate gauge pressures (100-3000 kpa) and temperatures...