XIAO-MEI LI,1 XU-HUI LIU,1 ELISABETH FILIPSKI,1 GÉRARD METZGER,1 PHILIPPE DELAGRANGE,2 JEAN-PHILIPPE JEANNIOT,3 AND FRANCIS LÉVI1 1Laboratoire ‘‘Rythmes Biologiques and Chronothérapeutique,’’ Institut du Cancer et d’Immunogénétique et Université Paris XI, Hôpital Paul Brousse, 94807 Villejuif Cedex; 2Institut de Recherches Internationales Servier, 92415 Courbevoie; and 3Technologie Servier, 450...

Welsh, Donald G., and Steven S. Segal. Role of EDHF in conduction of vasodilation along hamster cheek pouch arterioles in vivo. Am J Physiol Heart Circ Physiol 278: H1832– H1839, 2000.—We tested whether local and conducted responses to ACh depend on factors released from endothelial cells (EC) in cheek pouch arterioles of anesthetized hamsters. ACh was delivered from a micropipette (1 s, 500 nA...

... INTRODUCTION . EXPERIMENTAL First Irradiation .. Second Irradiation. CALCULATIONS ... First Irradiation. Second Irradiation. . CONCLUSIONS .•... ACKNOWLEDGEMENT . IS-184 CONTENTS 3

Rademaker, Miriam T., Vicky A. Cameron, Christopher J. Charles, Eric A. Espiner, M. Gary Nicholls, Christopher J. Pemberton, and A. Mark Richards. Neurohormones in an ovine model of compensated postinfarction left ventricular dysfunction. Am. J. Physiol. Heart Circ. Physiol. 278: H731–H740, 2000.—Clinical heart failure, often the result of myocardial infarction, may be preceded by a period of c...

Bertuglia, Silvia, and Antonio Colantuoni. Protective effects of leukopenia and tissue plasminogen activator in microvascular ischemia-reperfusion injury. Am. J. Physiol. Heart Circ. Physiol. 278: H755–H761, 2000.—Ischemia shifts the anticoaugulant/procoagulant balance of the endothelium in favor of activation of coagulation. We studied whether cheek pouch microcirculation of leukopenic hamster...

Ray, Ramesh M., Mary Jane Viar, Qing Yuan, and L. R. Johnson. Polyamine depletion delays apoptosis of rat intestinal epithelial cells. Am. J. Physiol. Cell Physiol. 278: C480–C489, 2000.—The polyamines spermidine, spermine, and their precursor putrescine are essential for cell growth and the regulation of the cell cycle. Recent studies suggest that excessive accumulation of polyamines favors ei...

Hirschfield, Wulf, Melanie R. Moody, William E. O’Brien, Anthony R. Gregg, Robert M. Bryan, Jr., and Michael B. Reid. Nitric oxide release and contractile properties of skeletal muscles from mice deficient in type III NOS. Am. J. Physiol. Regulatory Integrative Comp. Physiol. 278: R95–R100, 2000.—Skeletal muscle constitutively expresses both the type I (neuronal) and type III (endothelial) isof...

Delp, Michael D., Patrick N. Colleran, M. Keith Wilkerson, Matthew R. McCurdy, and Judy MullerDelp. Structural and functional remodeling of skeletal muscle microvasculature is induced by simulated microgravity. Am J Physiol Heart Circ Physiol 278: H1866–H1873, 2000.— Hindlimb unloading of rats results in a diminished ability of skeletal muscle arterioles to constrict in vitro and elevate vascul...

Yang, H. T., and Y. Feng. bFGF increases collateral blood flow in aged rats with femoral artery ligation. Am. J. Physiol. Heart Circ. Physiol. 278: H85–H93, 2000.—We tested the hypothesis that aged animals are as responsive as the young adult animals in expanding collateral vasculature under a similar treatment of basic fibroblast growth factor (bFGF). Two age groups of male Fischer 344 rats (1...

Miller, Kristy J., Deepa Thaloor, Sarah Matteson, and Grace K. Pavlath. Hepatocyte growth factor affects satellite cell activation and differentiation in regenerating skeletal muscle. Am. J. Physiol. Cell Physiol. 278: C174– C181, 2000.—Hepatocyte growth factor (HGF) is the only known growth factor that activates quiescent satellite cells in skeletal muscle. We hypothesized that local delivery ...