traditionally, peganum harmala seeds (p.h) have been extensively used in the asia region. we have previously reported the increase of fear behavior by systemic administration of p.h extract. here, we evaluated the effect of central administration of the extract on the fear behavior. method: methanolic extract of the plant's seeds (37% humidity) was prepared for the investigation. elevated ...

Peganum harmala L. (Zygophyllaceae) known locally as harmel is a medicinal plant. In traditional medicine, its seeds have long been used for therapeutic purposes because of their richness in β-carboline alkaloids. This study aimed to evaluate the maternal and developmental toxicity during pregnancy by daily IP administration 7.99 mg/kg/day (1/20 DL50) total alkaloids extract P.harmala’ seeds. T...

This article reports on an ethnopharmaceutical field study carried out among Turkish migrants in Cologne, western Germany, which recorded 79 botanical taxa and 115 plant-based preparations, encompassing 167 folk phytotherapeutical uses, as well as a few other biological (animal and mineral derived) remedies. One-fourth of the recorded remedies were represented by food-medicines. Half of the ing...

To understand plant evolution and diversification, information regarding chromosome number meiotic behavior is imperative. The present study was carried out to determine the count, behavior, pollen fertility, seed set of a medicinally important Peganum harmala. Two cytotypes, diploid tetraploid are growing in western Himalaya; cytotype (2n=2x=24) Kashmir Himalaya, (2n=4x=48) Trans Ladakh. Chrom...

background and objectives: because of toxical and hazardous properties of hexavalent chromium (cr(vi)), its removal by an economical and efficient method is necessary. the use of activated carbon, as an adsorbent, is a common and effective method for hexavalent chromium removal. thus the aim of this study was to produce granular and powdered activated carbon form peganum harmala and compare the...

based on the extensive application of peganum harmala (p.h) seeds in the asian traditional medicine, we tried to investigate its possible anxiety effect. method: the effect of p.h. extract inhalation was evaluated in adult male rats using elevated plus-maze apparatus. the humidity of prepared ethanol extract was 37%. animals in different groups (n=6) received 2, 4, 6, 12 or 18 gr/ml doses of th...

Objective: The present study was conducted to investigate antibacterial properties of fruit and flower of Peganum harmala. Material and Methods: Column chromatography, followed by preparative thin layer chromatography (TLC) was used for final purification. The structure of pure alkaloids was determined using spectroscopic methods (1H-N...