Paired Associated learning (PAL) as part of the Cambridge Neurological Test Battery (CANTAB) is a task of great potential for disease research. The initial interest in this task was sparked by studies of patients with Alzheimer’s disease (AD) or mild cognitive impairment (MCI), often viewed as a prodromal form of AD. AD patients were highly impaired on PAL, more importantly, so were a sub-popul...

OBJECTIVE The aim of the present study was to examine the effects of a new antipsychotic drug paliperidone palmitate on hemogram and coagulation parameters in rats. MATERIALS AND METHODS Experiments were performed on 22 female albino Wistar rats (8-12 weeks old). Control group was given drinking water as vehicle (0.3 mL). PAL-1 rats were given 1 mg/kg paliperidone palmitate (in 0.3 mL drinkin...

BACKGROUND Peer-assisted learning (PAL) has become a well-accepted teaching method within medical education. However, descriptions of on-ward PAL programs are rare. A focus group analysis of a newly established PAL program on an internal medicine ward was conducted to provide insights into PAL teaching from a student perspective. PURPOSE To provide insights into students' experiences regardin...

We report two studies examining the relations among three paired-associate learning (PAL) tasks (visual-visual, verbal-verbal, and visual-verbal), phoneme deletion, and single-word and nonword reading ability. Correlations between the PAL tasks and reading were strongest for the visual-verbal task. Path analyses showed that both phoneme deletion and visual-verbal PAL were unique predictors of a...

In this document the humanoid robot “Arabot” will be presented. Arabot was built by the company Pal Technology as research platform in the field of service robots. The hardware design has the primary goal to achieve good dynamic performance and extreme lightweight. The specifications of the first prototype are described below. Pal Technology wants to participate to Robocup 2006 in the humanoid ...

Exercise is vital to maintaining good health, but many people neglect to work out regularly or often enough. One reason is the lack of will to take part in physical activities. We believe that interactive technologies can play a role in providing entertaining and implicitly educational mechanisms that will help people pursue healthy physical activities. As an example to our approach we present ...

Cultured human umbilical vein endothelial cells release tissue plasminogen activator ft-PA) and type 1 plasminogen activator inhibitor (PAl-i ) in response to alpha thrombin stimulation. In order to study the mechanisms of thrombin stimulation, we measured changes in levels of mRNA for t-PA and PAl-i following exposure of endothelial cells to 3 U/mI alpha thrombin. Alpha thrombin causes a signi...

Although mitochondrial oxidative catabolism of fatty acid (FA) is a major energy source for the adult mammalian heart, cardiac lipotoxity resulting from elevated serum FA and enhanced FA use has been implicated in the pathogenesis of heart failure. To investigate the effects of intermediates of FA metabolism [palmitoyl-l-carnitine (Pal-car) and palmitoyl-CoA (Pal-CoA)] on mitochondrial function...