Aspect-oriented programming and the development of aspect-oriented languages are rapidly gaining momentum, and the advent of this new kind of programming language provides interesting challenges for compiler developers, both in the frontend semantic analysis and in the backend code generation. This paper is about the design and implementation of the abc compiler for the aspect-oriented language...

The ABC Transporter/Channel Superfamily The ATP-binding cassette (ABC) superfamily is probably the largest and most diverse family of proteins that mediate the selective movement of solutes across biological membranes. Many ABC proteins are of considerable clinical significance: human P-glycoprotein (P-gp) confers resistance of cancers to chemotherapeutic drugs, Pghl has a role in chloroquine r...

Dasatinib is a multikinase inhibitor in clinical trials for glioma, and thus far has failed to demonstrate significant efficacy. We investigated whether the ABC efflux transporters ABCG2 and ABCB1 expressed in the blood-brain barrier (BBB), are limiting the efficacy of dasatinib in the treatment of glioma using genetic and pharmacologic approaches. We utilized a genetic brainstem glioma mouse m...

The initial development and distribution of lymphocytes expressing surface IgM (sIgM) and of specific antigen-binding cells (ABC) were studied in the chicken in an attempt to gain information on the process by which B-cell diversity is generated. The antigens used were sheep erythrocytes (SE), keyhole limpet hemocyanin (KLH), and poly-L(Tyr, Glu)poly-D,L-Ala-poly-L-Lys (TGAL). The results indic...

Artificial Bee Colony (ABC) algorithm was firstly proposed for unconstrained optimization problems on where that ABC algorithm showed superior performance. This paper describes a modified ABC algorithm for constrained optimization problems and compares the performance of the modified ABC algorithm against those of state-of-the-art algorithms for a set of constrained test problems. For constrain...

The ATP binding cassette (ABC) proteins are a family of membrane transporters and regulatory proteins responsible for diverse and critical cellular process in all organisms. To date, there has been no attempt to investigate this class of proteins in the infectious parasite Trichomonas vaginalis. We have utilized a combination of bioinformatics, gene sequence analysis, gene expression and confoc...

As an approach to characterizing all human ATP-binding cassette (ABC) superfamily genes, a search of the human expressed sequence tag (EST) database was performed using sequences from known ABC genes. A total of 105 clones, containing sequences of potential ABC genes, were identified, representing 21 distinct genes. This brings the total number of characterized human ABC genes from 12 to 33. Th...

Activity-based costing (ABC) tries to allocate overhead costs to cost objects more accurately than traditional cost systems. However, since ABC proportionalizes overhead costs it is a heuristic. The paper uses simulations and mixedinteger programming to analyze the extent of the sub-optimality incurred by ABC-heuristics. While previous research has focused on ABC systems with a simple set of co...

Artificial Bee Colony (ABC) algorithm is considered new and widely used in searching for optimum solutions. This is due to its uniqueness in problem-solving method where the solution for a problem emerges from intelligent behaviour of honeybee swarms. This paper proposes the use of the ABC algorithm as a new tool for Data Mining particularly in classification tasks. Moreover, the proposed ABC f...

In recent years approximate Bayesian computation (ABC) methods have become popular in population genetics as an alternative to full-likelihood methods to make inferences under complex demographic models. Most ABC methods rely on the choice of a set of summary statistics to extract information from the data. In this article we tested the use of the full allelic distribution directly in an ABC fr...