نتایج جستجو برای: آزمون warm tail immersion

تعداد نتایج: 213901  

Journal: :African journal of traditional, complementary, and alternative medicines : AJTCAM 2009
Jeba Sunilson J Anbu P Jayaraj R Varatharajan John Thomas James Jisha M Muthappan

The ethanol and water extracts of Sansevieria trifasciata leaves showed dose-dependent and significant (P < 0.05) increase in pain threshold in tail-immersion test. Moreover, both the extracts (100 - 200 mg/kg) exhibited a dose-dependent inhibition of writhing and also showed a significant (P < 0.001) inhibition of both phases of the formalin pain test. The ethanol extract (200 mg/kg) significa...

Journal: :African journal of traditional, complementary, and alternative medicines : AJTCAM 2013
Xiaorong Li Jiangning Wang Lei Gao

The objective of this paper was to study the anti-inflammatory and analgesic effects of Radix Angelicae Pubescentis (R.A.P) ethanol extracts. Three classic anti-inflammatory models and two analgesic models were used in this research. In anti-inflammatory tests, all the extracts have a certain inhibition on the acute inflammation induced by xylene, however, 60% ethanol extract significantly inhi...

Background and Objective: Hyperalgesia is one of the marked clinical signs of patients with diabetes mellitus that affects their lifestyle. This study was conducted to assess the anti-nociceptive effect of chronic administration of curcumin in streptozotocin (STZ)-diabetic rats using formalin, hot tail immersion, and paw pressure tests. Materials and Methods: This study was conducted on 40 male...

احمدی, رحیم, عسگری, وحید ,

  Background : Various studies indicate that gonadal hormones exert modulatory effects on pain threshold. The aim of this study was to investigate the role of estradiol or progesterone in the response by female rats to thermal nociceptive stimulation.   Methods: In this laboratory experimental study, thirty 7 week old albino (Wistar) rats were randomly divided into control, sham and ovariectomi...

2017
Sumaira Ansari Sadia Arif Nousheen Mushtaq Ahsaan Ahmed Shamim Akhtar Rabya Munawar Huma Naseem Sadia Meer Zafar Saied Saify Muhammad Arif

In present study, some 4-piperidinopiperidine (PP) and 4-amino methylpiperidine (AMP) derivatives (PP1-3 and AMP4-9) have been synthesized to explore their analgesic potential. Activity of compounds evaluated by in-vivo thermal (tail immersion) method produced significant analgesia at different doses. Docking results explained good binding affinity of synthesized derivatives and potential inter...

Journal: :avicenna journal of medical biotechnology 0

methanolic extract of whole plant of amaranthus viridis l (meav), was screened for antinociceptive activity using acetic acid induced writhing test, hot plate test and tail immersion test in mice. in a similar way a screening exercise was carried out to determine the antipyretic potential of the extract using yeast induced pyrexia method in rats. administration of the extracts was applied to bo...

Journal: :Physiological and biochemical zoology : PBZ 2000
T B Watkins

The effects of acute and developmental temperature on maximum burst swimming speed, body size, and myofibrillar ATPase activity were assessed in tadpoles of the Pacific tree frog, Hyla regilla. Tadpoles from field-collected egg masses were reared in the laboratory at 15 degrees (cool) and 25 degrees C (warm). Body size, maximum burst swimming speed from 5 degrees to 35 degrees C, and tail myofi...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2005
Hyosang Lee Tohko Iida Atsuko Mizuno Makoto Suzuki Michael J Caterina

Transient receptor potential vanilloid 4 (TRPV4), a cation channel responsive to hypotonicity, can also be activated by warm temperatures. Moreover, TRPV4-/- mice reportedly exhibit deficits in inflammation-induced thermal hyperalgesia. However, it is unknown whether TRPV4 or related transient receptor potential channels account for warmth perception under injury-free conditions. We therefore i...

Journal: :research in pharmaceutical sciences 0
gabriel dapaah george asumeng koffuor priscilla kolibea mante inemesit okon ben

picralima nitida is used traditionally for management of cough. this study, therefore, investigated the antitussive, expectorant, and analgesic properties of the ethanolic seed extract of picralima nitida (pne), and ascertained its safety for use. presence of secondary metabolites, and safety of pne (10-2000 mg/kg) were evaluated by preliminary phytochemical screening, and by irwin’s test respe...

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