نتایج جستجو برای: آزمون پیری زودرس aat
تعداد نتایج: 125013 فیلتر نتایج به سال:
AIM To assess the possible relationship between serum alpha-1 antitrypsin (AAT) levels and anti-neutrophil cytoplasmic antibodies (ANCA) in autistic children with severe GI disease and to test the hypothesis that there is an association between low serum AAT levels, the presence of ANCA and inflammatory GI disease seen in some autistic children. SUBJECTS AND METHODS Serum from 40 autistic chi...
A review of the clinical manifestations of alpha(1)-antitrypsin (AAT) deficiency, including lung disease and liver disease, and risk factors affecting the rate of decline in lung function in AAT deficient patients.
BACKGROUND CD14, a receptor for lipopolysaccharides (LPS), is found in both a membrane-bound form (mCD14) and a soluble form (sCD14). It is suggested that sCD14 is mainly released from blood monocytes by serine protease-mediated shedding. Because alpha1-antitrypsin (AAT), an inhibitor of serine proteases, has been shown to regulate CD14 expression in human monocytes in vitro, we sought to inves...
Alpha-1 antitrypsin (AAT) deficiency remains an underrecognized genetic disease with predominantly pulmonary and hepatic manifestations. AAT is derived primarily from hepatocytes; however, macrophages and neutrophils are secondary sources. As the natural physiological inhibitor of several proteases, most importantly neutrophil elastase (NE), it plays a key role in maintaining pulmonary protease...
Alpha-1 antitrypsin (AAT) deficiency is well-suited as a target for human gene transfer. We performed a phase 1, open-label, dose-escalation clinical trial of a recombinant adeno-associated virus (rAAV) vector expressing normal (M) AAT packaged into serotype 1 AAV capsids delivered by i.m. injection. Nine AAT-deficient subjects were enrolled sequentially in cohorts of 3 each at doses of 6.9 x 1...
به منظور ارزیابی تأثیر تنش سرمایی و پیری تسریع شده بر شاخص های جوانه زنی و رشد گیاهچه پنج رقم کلزای hyola330، hyola401، hyola420، syn-3 و pr401/15e، آزمایشی در قالب طرح کاملا تصادفی با سه تکرار در شرایط آزمایشگاه اجرا شد. نتایج حاصل مشخص ساخت که ارقام از لحاظ درصد جوانه زنی، شاخص بنیه بذر، سرعت جوانه زنی و طول گیاهچه در شرایط جوانه زنی استاندارد، سرما و پیری تسریع شده دارای اختلاف معنی داری با ...
¯چکیده زمینه : تشخیص زودرس پراکلامپسی در کم کردن عوارض و مرگ و میر ناشی از آن نقش تعیین کننده ای دارد و یکی از روش های پیش بینی زودرس این بیماری، آزمون غلتیدن (Roll-over test) است. هدف : مطالعه به منظور تعیین ارزش پیش گویی آزمون غلتیدن در تشخیص زودرس پراکلامپسی انجام شد. مواد و روش ها : این مطالعه آینده نگر در سال 1378 در درمانگاه پرناتال بیمارستان امام خمینی تهران بر روی 140 زن باردار سالم که ...
In certain types of cancer, increased serum protease inhibitor levels were identified and clues showing that, serum levels of protease inhibitor could be used in the assessment of prognosis and dissemination of tumor were obtained. We aimed to reveal whether serum alpha-1-antitrypsin (AAT) and alpha-2-macroglobulin (AMG) levels of patients with lung cancer are related with histological type, cl...
Acute graft-versus-host disease (GvHD) is a major complication that prevents successful outcomes after allogeneic bone marrow transplantation (BMT), an effective therapy for hematological malignancies. Several studies demonstrate that donor T cells and host antigen-presenting cells along with several proinflammatory cytokines are required for the induction of GvHD and contribute to its severity...
Severe alpha-1 antitrypsin (AAT) deficiency is a proven genetic risk factor for COPD, but there is marked variation in the development of COPD among AAT deficient subjects. To investigate familial aggregation of lung function in subjects with AAT deficiency, we estimated heritability for forced expiratory volume in 1 s (FEV1) and FEV1/forced vital capacity (FVC) in 378 AAT deficient subjects fr...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید