Betula utilis, also known as Himalayan silver birch has been used as a traditional medicine for many health ailments like inflammatation, HIV, renal and bladder disorders as well as many cancers from ages. Here, we performed bio-guided fractionation of Betula utilis Bark (BUB), in which it was extracted in methanol and fractionated with hexane, ethyl acetate, chloroform, n-butanol and water. Al...

We evaluated the neuropharmacological profile of acetylated alphaand beta-amyrin (AcAMY) obtained by the acetylation of the isomeric mixture of alphaand beta-amyrin isolated from Protium heptaphyllum. Male Swiss mice were administered with AcAMY (2.5, 5, 10 and 25 mg/kg, i.p.), and anticonvulsant (pentylenetrazoleand pilocarpine-induced convulsions), sedative (barbiturate-induced sleep and open...

The present investigation aims at assessing the hepatoprotective effect of triterpene fraction isolated from the stem bark of Wrightia tinctoria (containing lupeol, b -amyrin and b -sitosterol) on CCl 4 -induced hepatotoxicity in the rat. CCl 4 (1.5 mg/kg, i.p) is a potent hepatotoxic agent which causes peroxidative degeneration of membrane lipids with the potential outcome of fatt...

The abuse of novel psychoactive substances (NPS) has been increasing dramatically worldwide since late 2000s. By the end of 2015, more than 560 NPS had been reported to the European Monitoring Centre for Drugs and Drug Addiction. Although the most popular compounds are synthetic cannabinoids and psychostimulatory derivatives of cathinone (so-called β-keto-amphetamines), novel synthetic opioids ...

A structural analysis of phytochemical constituents present in the ethanolic extract Mangifera indica fresh leaves were investigated to assert presence bioactive compounds corresponding reported antioxidant, antibacterial, antihyperglycemic, antidiabetic and anthelmintics properties plant. Extraction was carried out on homogenised using conventional soxhlet apparatus, with ethanol chosen select...

Sarcostemma acidum (Roxb.) Voigt is a valuable medicinal plant to treat number of diseases in India. Four compounds were isolated from the whole S. acidum. The structures characterized as Friedelin (1), ?-amyrin (2), ?-sitosterol (3) and 4?-Carboxy-4?-methyl-5?-cholesta-8,24-dien-3?-ol (4) by extensive spectroscopic (NMR, FT-IR mass) analysis compared their spectral data with literature. vitro ...