the main goal in endodontic treatment is to eradicate or at least reduce intraradicular microbial population to levels that are more compatible with periapical lesions healing process. since endodontic infections are polymicrobial in nature, intraradicular survival of endodontic microbiota and their pathogenic properties are influenced by a combination of their virulence factors. the purpose of...

background: suppressive therapy with levothyroxine for reducing the size of thyroid nodules has not been really accepted. the purpose of this study was to assess the effect of levothyroxine on the size of benign thyroid nodules. methods: forty patients with confirmed benign nodule were randomly divided into two groups. group i received 50?g/day levothyroxin for six months but group ii did not t...

background and objectives: significant progress has been made in treatment of hemophilia. ex-vivo gene therapy is going popular due to the capability of this method in using isogenic cells for genetic manipulation and reintroducing them into same host after proliferation. most gene therapy techniques use viral vectors, which usually harbor a strong and non-specific promoter (e.g. cmv early prom...

background: methadone is considered a long-acting opioid agonist which is widely used in the treatment of drug addiction. it is believed that opioids can cause erectile dysfunction (ed) by inhibiting gonadotropin and testosterone release. this study is aimed at defining the possible effects of conservative treatment with methadone on erectile dysfunction in the addicts. methods: a total of 382 ...

abstract: background : cyclic vomiting syndrome(cvs) is a disorder with dysmotility component and erythromycin is  a an antibiotic with prokinetic effect. this study aimed to evaluate the erythromycin efficacy in childhood cyclic vomiting syndrome methods : in this prospective study, 301 patients with final diagnosis of cvs enrolled in two separated groups. the first group received erythromycin...

objectives: loneliness is a common experience of people, regardless of gender, age, socio economic and cultural experience in the course of its life. the aim of this study was to examine the effectiveness of gestalt group therapy on the loneliness of alzheimer’s caregivers. methods: in an experimental study with a pre-post test design and control group, women participants were selected from alz...