Microspheres/microparticles constitute an important part of drug delivery system by virtue of their small size and efficient carrier characteristics. These delivery systems offer numerous advantages compared to conventional dosage forms, which include improved efficacy, reduced toxicity, improved patient compliance and convenience. The objective of the present investigation is to design and eva...

The influence of excipients on the disintegration times of tablets and the release of papaverine hydrochloride (PAP) from tablets were studied. Ten different formulations of tablets with PAP were prepared by direct powder compression. Different binders, disintegrants, fillers, and lubricants were used as excipients. The release of PAP was carried out in the paddle apparatus using 0.1 N HCl as a...

Acoustic emission before the failure of heterogeneous materials is studied as a function of applied hydrostatic pressure. A formula for the energy release is suggested, which is valid in the whole diapason of pressures, from zero to the critical pressure of rupture. This formula is obtained by employing the extrapolation technique of the self-similar approximation theory. The result is fitted t...

We investigate linear operators between C?-algebras which approximately preserve involution and orthogonality, the latter meaning that for some ?>0 we have ??(x)?(y)????x??y? all positive x,y with xy=0. establish structural properties of such maps concerning approximate Jordan-like equations almost commutation relations. In situations (e.g. when codomain is finite-dimensional), show ? can be ap...