BACKGROUND/AIMS
We determined the effects of age and sex on the blood pressure (BP) response to angiotensin II (Ang II) infusion and evaluated the potential mechanistic role of the thiazide-sensitive NaCl cotransporter (NCC) and the epithelial sodium channel (ENaC).
METHODS
Male and female mice (approximately 3 or 21 months of age) were infused with Ang II or control for 7 days.
RESULTS
Mal...
