Corynebacterium pseudotuberculosis is a gram-positive bacterium that causes caseous lymphadenitis in sheep and goats. However, despite the economic losses caused by caseous lymphadenitis, there is little information about the molecular mechanisms of pathogenesis of this bacterium. Genomic libraries constructed in bacterial artificial chromosome (BAC) vectors have become the method of choice for...

Aims: This study was aimed at investigating the microbial quality of air within confines nursery school children. Early exposure to these indoor pollutants can lead major public health concerns which include acute respiratory tract infections, allergies as well cancer.
 Study Design: Random sampling approach used in collection samples. Air samples were collected from two different classroo...

The incidence of the most common foodborne outbreaks reported by European Food Safety Authority and Centre for Disease Prevention Control during years 2015–2019 is described. Campylobacter spp., Salmonella Listeria monocytogenes, Yersinia enterocolitica are investigated microorganisms, symptomatology, food categories responsible human disease, as well some prevention measures important informat...

This study sought to understand the health risks of foodborne pathogens in fresh leafy vegetables that are grown and consumed locally Yaounde, Cameroon. Through a survey, 200 respondents were recruited relate possible food-related illnesses vegetable consumption. Additionally, total 168 samples consisting six 15 irrigated water from five sources collected farms local markets for microbiological...

BACKGROUND Caseous lymphadenitis (CLA) is an infectious disease that affects small ruminants and is caused by Corynebacterium pseudotuberculosis. This disease is responsible for high economic losses due to condemnation and trim of infected carcasses, decreased leather and wool yield, loss of sales of breeding stock and deaths from internal involvement. Treatment is costly and ineffective; the m...

Kansas witnessed an unprecedented outbreak in Corynebacterium pseudotuberculosis infection among horses, a disease commonly referred to as pigeon fever during fall 2012. Bayesian geostatistical models were developed to identify key environmental and climatic risk factors associated with C. pseudotuberculosis infection in horses. Positive infection status among horses (cases) was determined by p...

A large-scale DNA vaccination trial was performed with sheep to investigate whether an antigen targeted by CTLA-4 enhanced and accelerated the humoral immune response. Vaccination with genetically detoxified phospholipase D (DeltaPLD) has been shown to be effective, at least partially, against Corynebacterium pseudotuberculosis, the causal agent of caseous lymphadenitis in sheep. CTLA-4 binds t...

The aim of this study was to evaluate the Enterobacterial Repetitive Intergenic Consensus (ERIC-PCR) as a tool for molecular typing of C. pseudotuberculosis isolates from eight different hosts in twelve countries. Ninety-nine C. pseudotuberculosis field strains, one type strain (ATCC 19410T) and one vaccine strain (1002) were fingerprinted using the ERIC-1R and ERIC-2 primers, and the ERIC-1R+E...