نتایج جستجو برای: xenograft

تعداد نتایج: 23157  

2012
RUI WANG SHUKUI QIN YUQING CHEN YUMEI LI CHANGJIE CHEN ZISHU WANG RONGSHENG ZHENG QIONG WU

Standard chemotherapy for advanced NSCLC has reached a therapeutic plateau. More effective strategies must be explored. The purpose of this study was to evaluate the role of metronomic chemotherapy combined with an angiogenesis inhibitor in non-small cell lung cancer (NSCLC). A total of 114 BALB/c nude mice were inoculated subcutaneously with human NSCLC cells (A549), and when xenograft tumors ...

2018
Shuo Tu Xia-Li Zhang Hui-Fang Wan Yan-Qin Xia Zhuo-Qi Liu Xiao-Hong Yang Fu-Sheng Wan

To investigate the effects of taurine on cell proliferation and apoptosis, the human lung cancer A549 cell line and xenograft tumors in nude mice were used. The effects of taurine on cell proliferation and apoptosis were observed at time points of 24, 48 and 72 h after treatment using an MTT assay to detect the survival rate, and flow cytometry to detect the apoptotic rate. Western blot analysi...

2009
Baoan Chen Jian Cheng Yanan Wu Feng Gao Wenlin Xu Huilin Shen Jiahua Ding Chong Gao Qian Sun Xinchen Sun Hongyan Cheng Guohong Li Wenji Chen Ningna Chen Lijie Liu Xiaomao Li Xuemei Wang

In this paper we establish the xenograft leukemia model with stable multidrug resistance in nude mice and to investigate the reversal effect of 5-bromotetrandrine (5-BrTet) and magnetic nanoparticle of Fe(3)O(4) (MNP-Fe(3)O(4)) combined with daunorubicin (DNR) in vivo. Two subclones of K562 and K562/A02 cells were inoculated subcutaneously into the back of athymic nude mice (1 x 10(7) cells/eac...

2015
Matthew T. Cook Yayun Liang Cynthia Besch-Williford Sandy Goyette Benford Mafuvadze Salman M. Hyder

PURPOSE Clinical trials and epidemiological evidence have shown that combined estrogen/progestin hormone replacement therapy, but not estrogen therapy alone, increases breast cancer risk in post-menopausal women. Previously we have shown that natural and synthetic progestins, including the widely used synthetic progestin medroxyprogesterone acetate (MPA), increase production of a potent angioge...

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