نتایج جستجو برای: xdr

تعداد نتایج: 1279  

2017
Jun Chen Peng Peng Yixiang Du Yi Ren Lifeng Chen Youyi Rao Weihua Wang

BACKGROUND Emergence of multidrug- and extensively drug-resistant tuberculosis (M/XDR-TB) is a major hurdle for TB control programs especially in developing countries like China. Resistance to fluoroquinolones is high among MDR-TB patients. Early diagnosis of MDR/pre-XDR-TB is essential for lowering transmission of drug-resistant TB and adjusting the treatment regimen. METHODS Smear-positive ...

2015
Alpa Dalal Akshay Pawaskar Mrinalini Das Ranjan Desai Pralhad Prabhudesai Prashant Chhajed Sujeet Rajan Deepesh Reddy Sajit Babu T. K. Jayalakshmi Peter Saranchuk Camilla Rodrigues Petros Isaakidis

BACKGROUND While the high burden of multidrug-resistant tuberculosis (MDR-TB) itself is a matter of great concern, the emergence and rise of advanced forms of drug-resistance such as extensively drug-resistant TB (XDR-TB) and extremely drug-resistant TB (XXDR-TB) is more troubling. The aim of this study was to investigate the trends over time of patterns of drug resistance in a sample of MDR-TB...

2017
Abdulaziz Zorgani

Introduction: The prevalence of extensively drug resistance (XDR) Acinetobacter baumannii (AB) is rapidly progressing. The aim of this study was to determine the prevalence of XDR A. baumannii in Tripoli, Libya. Methods: AB isolates were identified and antibiotic susceptibility testing was performed using an automated system to determine the multidrug resistant organisms. XDR-AB was considered ...

Journal: :The West Indian medical journal 2011
M Arjomandzadegan M Sadrnia L K Surkova L P Titov

Resistance phenomenon in M tuberculosis is mainly based on decreased permeability of the bacterial envelope and function of effluent pumps. The regulatory gene of the whiB7 transcription determines drug resistance in these bacteria. Increases in WhiB7 protein activity induce transcription of resistance genes leading to intrinsic multidrug resistance. The aim of this work was to evaluate the whi...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014
Mayara L Bastos Hamidah Hussain Karin Weyer Lourdes Garcia-Garcia Vaira Leimane Chi Chiu Leung Masahiro Narita Jose M Penã Alfredo Ponce-de-Leon Kwonjune J Seung Karen Shean José Sifuentes-Osornio Martie Van der Walt Tjip S Van der Werf Wing Wai Yew Dick Menzies

BACKGROUND Individualized treatment for multidrug-resistant (MDR) tuberculosis and extensively drug-resistant (XDR) tuberculosis depends upon reliable and valid drug susceptibility testing (DST) for pyrazinamide, ethambutol, and second-line tuberculosis drugs. However, the reliability of these tests is uncertain, due to unresolved methodological issues. We estimated the association of DST resul...

2000
Jeffrey A. Meister Jeffrey S. Foster Michael Hicks

C static analysis tools often use intermediate representations (IRs) that organize program data in a simple, well-structured manner. However, the C parsers that create IRs are slow, and because they are difficult to write, only a few implementations exist, limiting the languages in which a C static analysis can be written. To solve these problems, we investigate two language-independent, on-dis...

2015
Poulomi Mukherjee Prasanta Ray Karmakar Saibendu Kumar Lahiri

Background:Emergence of drug resistant tuberculosis, particularly multi drug resistant TB (MDR-TB) and extensively drug resistant TB (XDR-TB) has become an obstacle to effective TB control in India. Objectives: To study the sociodemographic and clinical profile of MDR/XDR-TB patients in Kolkata. Methodology: A retrospective study was performed on MDR patients admitted in Jadavpur and Boral TB h...

2017
Meng-Yu Chen Yi-Chun Lo Wan-Chin Chen Kwei-Feng Wang Pei-Chun Chan

Recurrence after successful treatment for multidrug-resistant tuberculosis (MDR-TB) is challenging because of limited retreatment options. This study aimed to determine rates and predictors of MDR-TB recurrence after successful treatment in Taiwan. Recurrence rates were analyzed by time from treatment completion in 295 M DR-TB patients in a national cohort. Factors associated with MDR-TB recurr...

Background: This study was done to detect multidrug resistant (MDR) and extremely drug resistant (XDR) of Pseudomonas aeruginosa among strains isolated from patients in Tehran, Iran, due to importance of these phenotypes in treatment of human infections. Methods: Eighty eightP. aeruginosa were isolated from patients in Tehran, Iran, and identified by routine...

Journal: :iranian journal of pathology 2015
horieh saderi parviz owlia

background: this study was done to detect multidrug resistant (mdr) and extremely drug resistant (xdr) of pseudomonas aeruginosa among strains isolated from patients in tehran, iran, due to importance of these phenotypes in treatment of human infections. methods: eighty eightp. aeruginosa were isolated from patients in tehran, iran, and identified by routine methods and pcr for oprl gene. their...

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