objective: to determine the effects of topical administration of 20% oltipraz solution on histomorphometrical and stereological aspects of skin tissue in full thickness skin wounds in laboratory rats. methods: thirty-six male wistar portion rats (220±20 g) were randomly divided into three groups (n=12). on the first day of experimentation, a 1-cm 2 circular wound was made on the posterior surfa...

A 17-yr-old young woman was referred to our hospital with a 2-yr history of claudication of the lower extremities and severe arterial hypertension. Physical examination revealed significantly different blood pressures between both arms (160/92 and 180/95 mmHg) and legs (92/61 and 82/57 mmHg). The hematological and biochemical values were within their normal ranges, except for the increased eryt...

During combat operations, extremities continue to be the most common sites of injury with associated high rates of infectious complications. Overall, ∼ 15% of patients with extremity injuries develop osteomyelitis, and ∼ 17% of those infections relapse or recur. The bacteria infecting these wounds have included multidrug-resistant bacteria such as Acinetobacter baumannii, Pseudomonas aeruginosa...

introduction: impaired wound healing in diabetic patients is a major clinical problem, which is associated with significant morbidity and mortality. estrogen has positive effects on neoangiogenesis, reepithelialization and cell proliferation. in this research, effect of estrogen on wound healing in diabetic male rats was investigated. methods: this study was performed on male wistar rats (body ...

conclusions the crude hydroalcoholic extract of burdock root was found to cause better outcomes in the healing process, acute inflammation, and fibrosis on the 7th, 14th, and 21st day postoperatively. objectives in this experimental study, 36 male wistar rats each weighting approximately 200 - 220 g were studied in six groups, each with 6 animals for 21 days. hydroalcoholic extract of burdock r...

conclusions epo injection into the site of tibiofibular fractures may possibly accelerate healing. background erythropoietin (epo), in addition to its function as an erythropoiesis regulator has a regenerative activity on some nonhematopoietic tissues. animal studies have suggested a role for erythropoietin in bone healing. objectives the present study aimed to evaluate the effects of local epo...

sulfated polysaccharides have shown promising effects on wound healing processes along with many other biological activities. the sulfated polysaccharides extracted from two algae species habitats in persian gulf were studied in vivo for their effects on collagen formation and epidermal regeneration. the polysaccharides were purified from aqueous extracts of p. tetrastromatica and p. boergeseni...

background burns are still considered one of the most devastating conditions in emergency medicine affecting both genders and all age groups in developed and developing countries, resulting into physical and psychological scars and cause chronic disabilities. this study was performed to determine the healing effect of curcumin on burn wounds in rat. methods seventy female sprague-dawley 180-220...