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Low dose cyclophosphamide (CY) can augment the development of delayed-type hypersensitivity to primary antigens in patients with ad vanced cancer. In this paper, we have considered the hypothesis that the immunopotentiation is related to reduction of T-suppressor activity. Peripheral blood lymphocytes were collected and cryopreserved from 45 patients with metastatic malignancy before and then 3...

The objective of this observational field study was to investigate the effect of an alternative intermittent lighting program (13L: 5D: 1L: 5D – Trt) vs. standard lighting program (16L: 8D – Ctrl) on production performance of laying-hen parent flocks. Two houses of 15,000 Hy-Line brown parent-stock hens each were used for the comparative study. Hen-day egg production (HDEP), eggs per hen ho...

Lactococcus lactis â-phosphoglucomutase (â-PGM) catalyzes the interconversion of â-D-glucose 1-phosphate (â-G1P) and â-D-glucose 6-phosphate (G6P), forming â-D-glucose 1,6-(bis)phosphate (âG16P) as an intermediate. â-PGM conserves the core domain catalytic scaffold of the phosphatase branch of the HAD (haloalkanoic acid dehalogenase) enzyme superfamily, yet it has evolved to function as a mutas...

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The purpose of orthodontic treatment is to get a functional occlusion and a good aesthetic result. More and more patients require orthodontic treatment and the main motivation is the improvement of smile aesthetics. Over the years, numerous indices have been developed to rank or score the severity of a malocclusion relative to a preconceived orthodontic ideal, or in terms of treatment need. One...

supplemented with 10% horse serum. The cells grew ex ponentially with a doubling time of 16 to 17 hours, had a cell volume (mean ±S.E.) of 2313 ±89 cu /tm, and were cloned in soft agar with a cloning efficiency of 68.7 ±6.3%. Sensitivity to the alkylating agent nitrogen mustard (HN2) was comparable to that observed previously with LSI78Y murine lymphoblasts; the D0 (the dose of drug reducing...

Lung cancer was induced in rabbits by the instillation of chemical carcinogens into the lower bronchus, with the use of a bronchoscope. The rabbits were divided into 2 groups. Group 1 received a mixture of 3-methylcholanthrene (3-MCA) and 4-nitroquinoline 1-oxide in rabbit plasma, and Group 2 received 3-MCA alone in distilled water. Doses of 40 mg of 3-MCA and 0.4 mg of 4-nitroquinoline 1-oxide...

Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. The in situ n-type doping of Ge thin films epitaxial grown on Si substrates is limited to 1 Â 10 19 cm À3 by the ph...