Five experiments were conducted with young, male, crossbred chicks to investigate the effects of experimental Eimeria acervulina infection on the efficacy of supplemental Cu and (or) methionine when added to a corn-soybean meal diet. Duodenal coccidiosis (due to E. acervulina) and supplemental Cu (500 and 750 mg/kg) depressed weight gain and efficiency of feed utilization. Supplemental Cu incre...

where the biting rate, mortality hazard (hence daily survival probability) and duration of the sporogonic cycle depend on temperature T (see Supplemental Material, Table 1) (Martens 1998) and all other parameters are defined in Supplemental Material, Table 2 (with baseline numerical values in Supplemental Material, Table 3). Vector parameters are estimated for Anopheles maculipennis (Martens 19...

Type 1 ryanodine receptor (RyR1) releases Ca2+ ions from the sarcoplasmic reticulum of skeletal muscle to initiate contraction. Multiple endogenous and exogenous effectors activate RyR1. Cryo-electron microscopy has identified binding sites three co-activators Ca2+, ATP caffeine, however, mechanism co-regulation synergy between these activators remains be determined. Here, we tested hypothesis ...

In a pilot group of 20 sequential patients who underwent metrizamide lumbar myelography, three modifications in technique were compared: (1) a "30" min delayed frontal projection, (2) supine projection of the conus medullaris, and (3) horizontal beam oblique views of the lumbosacral theca. The study showed much better opacification of the lowermost lumbar and the sacral root sleeves by delayed ...

Abstract Introduction Calmodulin (CaM) is a highly conserved mediator of calcium (Ca2+) dependent signalling. Its flexible structure allows CaM to bind and modulate many targets, including cardiac ion channels. Genotyping has revealed several mutations associated with congenital disorders heart rhythm, known as long QT-syndrome (LQTS). LQTS patients suffer from prolonged ventricular recovery ti...