نتایج جستجو برای: wif1 و ctsl1

تعداد نتایج: 760751  

2011
Musa Drini Nicholas C. Wong Hamish S. Scott Jeffrey M. Craig Alexander Dobrovic Chelsee A. Hewitt Christofer Dow Joanne P. Young Mark A. Jenkins Richard Saffery Finlay A. Macrae

BACKGROUND Hyperplastic Polyposis Syndrome (HPS) is a condition associated with multiple serrated polyps, and an increased risk of colorectal cancer (CRC). At least half of CRCs arising in HPS show a CpG island methylator phenotype (CIMP), potentially linked to aberrant DNA methyltransferase (DNMT) activity. CIMP is associated with methylation of tumor suppressor genes including regulators of D...

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