The present study is concerned with the production of antitumor antibiotic by Streptomyces capoamus in batch fermentation. Antibiotic activity was tested against Bacillus subtilis by cylinder plate method. Different culture media were screened and M3 medium consisting of glucose (10.0 g/L), yeast extract (1.0 g/L), meat extract (4.0 g/L), peptone (4.0 g/L) and NaCl (2.0 g/L) was found to be the...

Increased production of sinefungin, a very potent antifungal and antiparasitic nucleoside antibiotic was achieved by medium and strain improvement. When soybean-meal, dextrin and yeast extract were added as carbon and nitrogen sources to the fermentation medium, instead of corn steep liquor, soya-oil and glucose; the antibiotic yield increased from 40 micrograms/ml to 126 micrograms/ml with low...

Production of lovastatin and microbial biomass by Aspergillus terreus ATCC 20542 were influenced by the type of the carbon source (lactose, glycerol, and fructose) and the nitrogen source (yeast extract, corn steep liquor, and soybean meal) used and the C:N mass ratio in the medium. Use of a slowly metabolized carbon source (lactose) in combination with either soybean meal or yeast extract unde...

In this work, oil mill wastewater (OMW), a residue generated during olive oil extraction, was evaluated as an inducer of rhamnolipid production. Using a medium containing as sole ingredients corn steep liquor (10%, v/v), sugarcane molasses (10%, w/v) and OMW (25%, v/v), Pseudomonas aeruginosa #112 produced 4.5 and 5.1g of rhamnolipid per liter in flasks and reactor, respectively, with critical ...

During the course of a screening program for antibiotics produced by a Saccharothrix, two new kinamycins 1 and 2 have been isolated from cultured broth of strain MI293-N4. They inhibit the growth of Gram-positive bacteria and neoplastic cells. This paper describes the production, isolation, purification and the structure elucidation of the antibiotics. Some physicochemical properties and biolog...

Sir: A new indolocarbazole antibiotic SF-2370 has been found in the culture broth of Actinomadura sp. SF-2370 which was isolated from a soil sample collected at Shimizu, Shizuoka Prefecture, Japan. The antibiotic is weakly active against some bacteria and fungi. In this communication, the isolation, characterization, and structural elucidation by the spectral studies are reported. Actinomadura ...

One metabolism trial and 2 finishing trials were conducted to evaluate the effects of adding corn bran and steep liquor (steep) in replacement of dry-rolled corn (DRC) on diet digestibility, cattle performance, and nutrient mass balance in open feedlot pens. The metabolism trial (Exp. 1) used 8 ruminally cannulated heifers in a 4 × 4 Latin square design and the 2 finishing trials used 128 steer...

The drive for renewable energy as an alternative to fossil fuel is on the increase globally. Modeling a process crucial increasing monitoring and control of plant efficiency ultimate objective optimal biorefinery operations. This study aims develop compare models that best predict fermentation parameters bioethanol production using corn-steep liquor (CSL) media supplement. response surface meth...

One metabolism trial and 2 finishing trials were conducted to evaluate the effects of adding corn bran and steep liquor (steep) in replacement of dry-rolled corn (DRC) on diet digestibility, cattle performance, and nutrient mass balance in open feedlot pens. The metabolism trial (Exp. 1) used 8 ruminally cannulated heifers in a 4 × 4 Latin square design and the 2 finishing trials used 128 steer...