CONTEXT Rapid increases in access to the Internet have made it a viable mode for public health intervention. No controlled studies have evaluated this resource for weight loss. OBJECTIVE To determine whether a structured Internet behavioral weight loss program produces greater initial weight loss and changes in waist circumference than a weight loss education Web site. DESIGN Randomized, co...

BACKGROUND AND OBJECTIVE The benefits of weight reduction for musculoskeletal disorders are well understood. Steep declines in muscle mass following considerable weight reduction can decrease muscle strength and, consequently, physical performance. However, only a limited number of studies have examined the changes in muscle mass and strength in the context of interventional weight reduction pr...

The current study aimed to investigate reasons for supporting harm reduction approaches to treating drug addiction. The study used Brickman et al.'s (1982) models of helping as a framework to determine the relationship between where a participant attributed the responsibility for the problem and solution to drug addiction and support for particular approaches to treating drug addiction. It was ...

BACKGROUND Research has shown that meal replacement calorie reduction combined with lifestyle change can more than double the weight loss seen with other diets. However, its widespread acceptance by physicians has been limited, perhaps waiting on evidence that patients are successful in keeping lost weight off. METHODS Obese patients (108.4 ± 25.7 kg, BMI 38.1 ± 7.9 kg/m2) used a diet of meal...

OBJECTIVE To evaluate the validity of a new lipid-based index (Disse index) in assessing insulin sensitivity (IS) compared with the hyperinsulinemic-euglycemic (HIEG) clamp in overweight and obese, non-diabetic, postmenopausal women, before and after a weight loss intervention. RESEARCH DESIGN AND METHODS Association between Disse index and the HIEG clamp was evaluated in 86 non-diabetic post...