PURPOSE Epithelial to mesenchymal transitions are vital for tumor growth and metastasis. Several inducers of epithelial to mesenchymal transition are transcription factors that repress E-cadherin expression, such as Snail, Slug, and Twist. In this study, we aimed to examine the expression of these transcription factors in pancreatic cancer. EXPERIMENTAL DESIGN The expression of Snail, Slug, a...

objective: during the past decade, the importance of biomarker discovery has been highlighted in many aspects of cancer research. biomarkers may have a role in early detection of cancer, prognosis and survival evaluation as well as drug response. cancer-testis antigens (ctas) have gained attention as cancer biomarkers because of their expression in a wide variety of tumors and restricted expres...

Objectives: To compare the performance of chest CT and Real-Time Reverse Transcription-Polymerase Chain Reaction (RTPCR) in initial diagnostic assessment coronavirus disease COVID-19 patients during pandemic. Methods& Results:In this study we have included 209 clinically suspected cases COVID-19from Government Medical College, Nagpur who undergone both HRCT RT-PCR. In our study, 3.35% were ...

During January and February 2001, an outbreak of febrile illness associated with altered sensorium was observed in Siliguri, West Bengal, India. Laboratory investigations at the time of the outbreak did not identify an infectious agent. Because Siliguri is in close proximity to Bangladesh, where outbreaks of Nipah virus (NiV) infection were recently described, clinical material obtained during ...

Several experimental approaches were used to construct a detailed transcriptional profile of the phylogenetically conserved ftsZ cell division gene cluster in both Mycoplasma genitalium and its closest relative, Mycoplasma pneumoniae. We determined initiation and termination points for the cluster, as well as an absolute steady-state RNA level for each gene. Transcription of this cluster in bot...