J. L. Gunter, M. A. Bernstein, B. J. Borowski, J. P. Felmlee, D. J. Blezek, R. P. Mallozzi, J. R. Levy, N. Schuff, C. R. Jack, Jr. 1 Mayo Clinic and Foundation, Rochester, MN, United States, GE Global Research, Niskayuna, NY, United States, The Phantom Laboratory, Salem, NY, United States, UC San Francisco, San Francisco, CA, United States Introduction: The Alzheimer's Disease Neuroimaging Init...

conclusion considering the similar diagnostic efficacy of all voxel sizes, 300 µm voxel size can be used with adequate efficacy for detection of external root resorption defects with minimal patient radiation dose and the shortest scanning time. background selecting a voxel size that yields minimal radiation dose with no significant compromise of the diagnostic accuracy of cone beam computed to...

PURPOSE In this work, we propose a new method of calibrating cone beam computed tomography (CBCT) data sets for radiotherapy dose calculation and plan assessment. The motivation for this patient-specific calibration (PSC) method is to develop an efficient, robust, and accurate CBCT calibration process that is less susceptible to deformable image registration (DIR) errors. METHODS Instead of m...

HighlY constrained backPRojection (HYPR) is a promising image-processing strategy with widespread application in time-resolved MRI that is also well suited for PET applications requiring time series data. The HYPR technique involves the creation of a composite image from the entire time series. The individual time frames then provide the basis for weighting matrices of the composite. The signal...

Abstract The simulation of subtractive manufacturing processes has a long history in engineering. Corresponding predictions are utilized for planning, validation and optimization, e.g., CNC-machining processes. With the up-rise flexible robotic machining advancements computational algorithmic capability, coupled machine-process behaviour complex large workpieces is within reach. These simulatio...

Longitudinal and multi-site clinical studies create the imperative to characterize and correct technological sources of variance that limit image reproducibility in high-resolution structural MRI studies, thus facilitating precise, quantitative, platform-independent, multi-site evaluation. In this work, we investigated the effects that imaging gradient non-linearity have on reproducibility of m...

Chronic airway disease causes structural changes in the lungs including peribronchial thickening and airway dilatation. Multi-detector computed tomography (CT) yields detailed near-isotropic images of the lungs, and thus the potential to obtain quantitative measurements of lumen diameter and airway wall thickness. Such measurements would allow standardized assessment, and physicians to diagnose...

Introduction There is significant interest in evaluating the performance and reliability of white matter fiber tractography algorithms. Diffusion tensor imaging (DTI) approach [1] is a powerful tool for non-invasive investigation of microstructure and has been successfully applied to detect different white matter diseases [2]. DTI-based fiber tracking gives insights into the complex architectur...