PURPOSE This study represents a first step toward the evaluation of possible compositional differences in meibum from normal donors (Mn) and donors with meibomian gland dysfunction (Md) by (1)H-NMR spectroscopy. The results highlight the applicability of (1)H-NMR spectroscopy for the quantitative analysis of waxes, cholesteryl esters, and glycerides in meibum lipid (ML). METHODS Meibum was ob...

OBJECTIVE To identify age-related changes in human meibomian glands that may be associated with meibomian gland dysfunction (MGD). METHODS Excess eyelid tissue from 36 patients (age range, 18-95 years, 19 female, 17 male) who underwent canthoplasty procedures were used. Dermatologic history, age, and presence of MGD were recorded. Samples were frozen, sectioned, and stained with specific anti...

BACKGROUND Relative to Western women, Korean women show several differences in breast-related characteristics, including higher rates of dense breasts and small breasts. We investigated how mammographic composition and breast size affect the glandular dose during full-field digital mammography (FFDM) in Korean women using a radiation dose management system. METHODS From June 1 to June 30, 201...

Mixed gonadal dysgenesis (MGD) is a disorder of sexual development that typically has a mosaic 45,X/46,XY karyotype. A 1-year-old infant with 46,XY identified by peripheral blood karyotype demonstrated clinical manifestations and gonadal pathologic features of MGD. Fluorescence in situ hybridization (FISH) for X and Y chromosomes and immunofluorescence for SRY along with testicular and ovarian ...

We analyze the effective field equations of Randall-Sundrum braneworld coupled with a Klein-Gordon scalar through minimal geometric deformation decoupling method (MGD-decoupling). introduce two different ways to apply MGD-decoupling obtain new solutions for this enlarged system. also compare behavior those obtained directly from Randall-Sumdrum without coupling field.

The Mouse Genome Database (MGD) is the community database resource for the laboratory mouse, a key model organism for interpreting the human genome and for understanding human biology and disease (http://www.informatics.jax.org). MGD provides standard nomenclature and consensus map positions for mouse genes and genetic markers; it provides a curated set of mammalian homology records, user-defin...

Evaporative dry eye has gained increasing interest in recent years in academia, pharmaceutical, and medical device industries. The main cause of this type of dry eye is attributed to meibomian gland dysfunction (MGD). MGD is a diffuse abnormality of the meibomian glands characterised by terminal duct obstruction and eventually leading to signs and symptoms of dry eye. There have been only a few...

Meibomian gland dysfunction (MGD) may well be the leading cause of dry eye disease throughout the world. Although this condition affects the health and well-being of millions of people, there is no global consensus on the definition, classification, diagnosis, or therapy for MGD. To achieve such a consensus, the Tear Film and Ocular Surface Society (TFOS; http://www.tearfilm.org), a nonprofit o...

OBJECTIVES/HYPOTHESIS The prevalence of multiglandular disease (MGD) of the parathyroid has been reported to be higher in patients with primary hyperparathyroidism and low baseline intact parathyroid hormone (PTH) levels (<100 pg/mL). Low baseline PTH is associated with lower localization rate and positive predictive value with both preoperative sestamibi and ultrasound. This study sought to ev...