Time series clustering algorithms have been widely used to mine the clustering distribution characteristics of real phenomena. However, these algorithms have several limitations. First, they depend heavily on prior knowledge. Second, the algorithms do not simultaneously consider the similarity of spatial locations, spatial-temporal attribute values, and spatial-temporal attribute trends (trends...

BACKGROUND The lysophosphatidic acid LPA₁ receptor regulates plasticity and neurogenesis in the adult hippocampus. Here, we studied whether absence of the LPA₁ receptor modulated the detrimental effects of chronic stress on hippocampal neurogenesis and spatial memory. METHODOLOGY/PRINCIPAL FINDINGS Male LPA₁-null (NULL) and wild-type (WT) mice were assigned to control or chronic stress condit...

OBJECTIVE The present study explored the three-dimensional spatial arrangements of the neurons and glial cells within the medial prefrontal cortex (mPFC) of rats. METHODS It evaluated the arrangement for differences after stress with or without treatment with curcumin and sertraline using second-order stereology. Orientator method was applied to obtain isotropic uniform random sections of mPF...

This paper presents an interactive volume modeling method that constructs skeletal muscles from an existing volumetric dataset. Our approach provides users with an intuitive modeling interface and produces compelling results that conform to the characteristic anatomy in the input volume. The algorithmic core of our method is an intuitive anatomy classification approach, suited to accommodate sp...

This paper presents a new architecture of database to deal with the complex structure and large volume of the spatial data. The object-oriented technology, which has the powerful modeling ability to describe the complex objects, is used to model the spatial objects. The massive storage that is base on the tertiary storage device is preferred to the large volume of spatial data. The deductive ru...

This article describes an image segmentation procedure applied over magnetic resonance (MR) data-images. The applied technique is based on a contour propagation process deened by an energy minimization analysis. The nal contour of each volume of the heart is deened by a propagation process (spline deformable curve) added to a re-sampling procedure which increases the number of control points. T...

The hippocampus of birds and mammals plays a crucial role in spatial memory and navigation. The hippocampus exhibits plasticity in adulthood in response to diverse environmental factors associated with spatial demands placed on an animal. The medial and dorsal cortices of the telencephalon of squamate reptiles have been implicated as functional homologues to the hippocampus. This study sought t...

The relationship between cerebral morphology and the expression of dopamine receptors has not been extensively studied in humans. Elucidation of such relationships may have important methodological implications for clinical studies of dopamine receptor ligand binding differences between control and patient groups. The association between cerebral morphology and dopamine receptor distribution wa...

The measurement of rapid regional lung volume changes by electrical impedance tomography (EIT) could determine regional lung function in patients with obstructive lung diseases during pulmonary function testing (PFT). EIT examinations carried out before and after bronchodilator reversibility testing could detect the presence of spatial and temporal ventilation heterogeneities and analyse their ...