Objective(s) Cigarette and nicotine enhances embryogenesis, fertility, pregnancy loss and ultrastructure alterations of oocyte. This study was performed to determine the effect of daily supplementation of vitamin E on oocytes apoptosis in nicotine-treated mice. Materials and Methods In this experimental study, 24 NMARI adult female mice were randomly allocated into four experimental groups. ...

Because high plasma concentrations of homocysteine constitute an enhanced risk for premature coronary heart disease, it is necessary to establish a reference range for normal concentrations of plasma homocysteine. The frequency distribution of plasma homocysteine concentrations tails to the right, and the nonparametric approach is unsatisfactory for defining a normal plasma homocysteine referen...

1 Departments of Medicine, Pediatrics, and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, United States of America, 2 Sabin Vaccine Institute and Texas Children’s Hospital Center for Vaccine Development, Houston, Texas, United States of America, 3 Human Development Department, World Bank, Washington, D.C., United States of ...

Zn supplementation has shown inconsistent effects on respiratory morbidity in young children in developing countries. Few studies have focused on upper respiratory tract infection (URTI), a frequent cause of morbidity in this group, and potential benefit from Zn supplementation or factors that influence its efficacy. We investigated the effects of Zn supplementation on URTI before and after vit...

OBJECTIVE To investigate the effect of vitamin A supplementation and BCG vaccination at birth in low birthweight neonates. DESIGN Randomised, placebo controlled, two by two factorial trial. SETTING Bissau, Guinea-Bissau. PARTICIPANTS 1717 low birthweight neonates born at the national hospital. INTERVENTION Neonates who weighed less than 2.5 kg were randomly assigned to 25 000 IU vitamin...

Vitamin D is a fat-soluble steroid hormone that activates vitamin D receptor to regulate multiple downstream signaling pathways and transcription of various target genes. There is an association between vitamin D deficiency and increased risk for cardiovascular disease. However, most of the studies are observational and associative in nature with limited data on clinical application. Thus, ther...

OBJECTIVE The aim of this study was to review the effects of vitamin D supplementation on depressive symptoms in randomized controlled trials. Although low vitamin D levels have been observationally associated with depressive symptoms, the effect of vitamin D supplementation as an antidepressant remains uncertain. METHODS MEDLINE, CINAHL, AMED, PsycINFO, Scopus, The Cochrane Library, and refe...

Methionine deficiency in the presence of a high-fat, high-cholesterol diet aggravates atherogenesis in the cockerel. High-protein, high-vitamin supplementation suppresses the atherogenic effect of a cholesterol-fat-containiiig diet. High-protein supplementation alone had a suppressive effect; high-vitamin supplementation had no effect. However, the combined protein and vitamin supplement was th...