Antiatherogenic Effect of Peripheral Adiposity? To the Editor: Tankó et al1 observed that peripheral adiposity in elderly women may be associated with a relatively reduced risk of insulin resistance, dyslipidemia, and vascular calcification. They suggested that this benefit reflects an antiatherogenic effect of peripheral fat. However, we believe their findings support the concept that subtly i...

OBJECTIVE We conducted a prospective study among Japanese Americans of diabetes incidence in relation to visceral and regional adiposity, fasting insulin and C-peptide, and a measure of insulin secretion, because little prospective data exist on these associations. RESEARCH DESIGN AND METHODS Baseline variables included plasma glucose, C-peptide, and insulin measured after an overnight fast a...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Ismail N, Nour ElDin Abd ElBaky AM, Hassan Ragab S, Ibrahim M. The relationship between the Chinese visceral adiposity index and presence of nonalcoholic fatty liver disease in obese children – a pilot study. Pediatria Polska - Polish Journal Paediatrics. 2022. doi:10.5114/polp.2022.120103. APA Ismail, N., ElBaky,...

OBJECTIVE Because vitamin D deficiency is associated with a variety of chronic diseases, understanding the characteristics that promote vitamin D deficiency in otherwise healthy adults could have important clinical implications. Few studies relating vitamin D deficiency to obesity have included direct measures of adiposity. Furthermore, the degree to which vitamin D is associated with metabolic...

CONTEXT The risk of type 2 diabetes mellitus is heterogeneous among obese individuals. Factors that discriminate prediabetes or diabetes risk within this population have not been well characterized. A dysfunctional adiposity phenotype, characterized by excess visceral fat and insulin resistance, may contribute to diabetes development in those with obesity. OBJECTIVE To investigate association...

In addition to lipoatrophy of the subcutaneous fat compartment and lipohypertrophy of the breasts and dorsocervical fat pad, excess visceral fat is considered to be part of human immunodeficiency virus (HIV)-associated lipodystrophy. Because of associations between visceral adiposity and atherosclerotic risk and undesirable clinical and psychological effects, therapies for this morphological al...

Myotonic dystrophy 1 (MD1) is caused by a CTG expansion in the 3'-unstranslated region of the myotonic dystrophy protein kinase (DMPK) gene. MD1 patients frequently present insulin resistance and increased visceral adiposity. We examined whether DMPK deficiency is a genetic risk factor for high-fat diet-induced adiposity and insulin resistance using the DMPK knockout mouse model. We found that ...

Cardiac and hepatic phenotype of diabetes in the presence and the absence of obesity mechanistic role of ectopic/visceral adiposity Eylem Levelt, Michael Pavlides, Masliza Mahmod, Catherine Kelly, Joanne Sellwood, Sheena Thomas, Jane M Francis, Jurgen E Schneider, Chris Rodgers, William T Clarke, Nikant Sabharwal, Charalambos Antoniades, Kieran Clarke, Theodoros D Karamitsos, Oliver Rider, Stef...

This study aimed to investigate the association between different anthropometric measures of obesity and clinicopathological characteristics in Chinese patients with clinically localized prostate cancer (PCa). A total of 734 patients with clinically localized PCa who underwent radical prostatectomy (RP) were included in this study. Clinical and pathological data from each patient were collected...

Visceral obesity is more common in the Arab population and more closely related to morbidity, including diabetes and related cardiovascular diseases (CVD). Possible mechanisms that link visceral fat/obesity to diabetes and CVD complications include inflammation and increased oxidative stress; however, few data are available from the Arab population. Our aim was to determine whether increased ad...