As Virulence is approaching its 3 year anniversary, we would like to take this opportunity to highlight the most recent developments and the course of the journal. In June this year, Thomson Reuters (formerly ISI) Web of Knowledge released the first impact factor (IF) for Virulence: 2.264. Certainly we have some way to go in order to reach our goals but this is a positive first step. We are ded...

Cell-to cell communication occurs via a signaling pathway referred to as quorum sensing. There are four main types of these systems according to the chemical nature of signal molecules used by microorganisms to elicit expression of target genes in response to environmental stimuli or need of microbial communities. Type I system acts by using acyl homoserine lactones as signals to trigger the ex...

Multiple infections are known to affect virulence evolution. Some studies even show that coinfections may decrease the overall virulence (the disease-induced mortality of a coinfected host). Yet, epidemiological studies tend to overlook the overall virulence, and within-host models tend to ignore epidemiological processes. Here, I develop an epidemiological model where overall virulence is an e...

the aim of this study was to isolate escherichia coli from chickens and to determine the presence of the eaea gene, a virulence factor detected in escherichia coli, in the isolates by polymerase chain reaction (pcr). different chicken organs (lung, liver and spleen) were inoculated onto blood agar and biochemical tests were performed on the suspicious isolates. escherichiacoliwas isolated from ...

Many pathogenic microbes have multiple virulence factors that can cause damage to the host and thus contribute to an overall virulence phenotype for that organism. Although current techniques are suitable for demonstrating that a particular microbial characteristic contributes to virulence, no formal approach for defining the relative contributions of multiple virulence factors to overall virul...

Brine shrimp are aquatic crustaceans belonging to a genus of Artemia. This organism is widely used for testing the toxicity of chemicals. In this study, brine shrimp were evaluated as an infection model organism to study bacterial virulence. Artemia nauplii were infected with various pathogenic bacteria, such as Vibrio vulnificus, Pseudomonas aeruginosa, Burkholderia vietnamiensis, Staphylococc...

In recent years, the role of bacterial sRNAs in adversity tolerance and pathogens has attracted increasing attention. A great number virulence-related were reported a variety human pathogens. However, only few from aquatic reported. our previous study, novel sRNA, sR158, was identified Edwardsiella piscicida, an important pathogen, but its function remains unknown. same we also type II TA syste...

In fish, bacteriosis has been widely linked with Aeromonas species, but co-infection by these bacteria little addressed. The aims of this study were to report on an outbreak disease in pirarucu Arapaima gigas caused and investigate experimental characterize resistance profile, virulence factors phenotypic molecular differentiation. Fish samples clinical signs collected used co-infection. bacter...

The increase in multidrug-resistant pathogens has created new anti-pathogenic and anti-virulence compounds. This is because of the behavioural changes bacteria acquire, such as increased antibiotic resistance virulence capacity. social behaviour maintained through a signalling transduction pathway called Quorum sensing. present study aims to evaluate inhibition quorum sensing Bacillus subtilis ...