OBJECTIVE The aim of the present study was to evaluate the long-term hearing during "wait and scan" management of vestibular schwannomas. SUBJECTS During a 33-year period, from 1976 to 2008, 1,144 patients with vestibular schwannoma were allocated to observation by the wait and scan policy, with annual magnetic resonance imaging and audiologic examination. Two complete pure-tone and speech di...

Neurofibromatosis type 2 is characterized by the development of multiple nervous system tumors. This disorder is also called multiple inherited schwannomas, meningiomas, and ependymomas syndrome. In this report, we discuss the magnetic resonance imaging findings in a patient with Neurofibromatosis type 2 who had right and left vestibular and trigeminal schwannomas, unilateral facial schwannoma,...

The concurrent presence of multiple primary brain tumours with different histological characteristics is very rare. A case of dual intracranial benign tumours comprising pituitary adenoma and vestibular schwannoma is described. The aetiology and genetic association of these pathologies is explored and the literature of multiple intracranial tumours of different cell types is reviewed.

OBJECTIVES To compare different methods of measuring tumor growth after resection of vestibular schwannoma and to identify predictors of growth. STUDY DESIGN Retrospective case review. SETTING Tertiary referral center, inpatient surgery with ambulatory follow-up. PATIENTS All patients who underwent vestibular schwannoma resection by the senior author from September 1991 to April 2012 and ...

OBJECT Vestibular schwannomas (VS) are common benign tumors of the vestibular nerve that cause significant morbidity. The current treatment strategies for VS include surgery or radiation, with each treatment option having associated complications and side effects. The transcriptional landscape of schwannoma remains largely unknown. METHODS In this study the authors performed gene-expression p...

Surgical treatment of vestibular schwannoma is targeted at complete removal with preserved neurological function. Complete removal may cause significant deficits, whereas subtotal tumor removal is associated with a high recurrence rate. The present study assessed the risk of tumor recurrence and postoperative facial nerve function in relation to the extent of surgical resection by reviewing the...

Intralabyrinthine schwannoma (ILS) is a rare benign tumor that affects the ends of cochlear and vestibular nerves. In a majority of the cases, it occurs with unilateral progressive sensorineural hearing loss. Less frequent symptoms include tinnitus, imbalance, vertigo, or fullness. The advent of magnetic resonance imaging allows early diagnosis and enables an appropriate therapeutic protocol. T...

In this study, we examined the effect of example cases with confounding values on decision trees constructed for six otoneurological diseases involving vertigo. The six diseases were benign positional vertigo, Menière’s disease, sudden deafness, traumatic vertigo, vestibular neuritis, and vestibular schwannoma. Patient cases with confounding values were inserted into original vertigo data and d...