Chronic treatment with haloperidol for 3 to 5 weeks (0.5 mg/kg, daily) resulted in significant increases of homovanillic acid (HVA) content in dorsal and orbital frontal cortex and in cingulate cortex. No change in HVA was seen in the olfactory cortex, basal ganglia, cisternal cerebrospinal fluid or plasma of animals chronically treated with haloperidol. Treatment with a single weekly dose of f...

The sources of error and the optivial design of an anterior chamber infusion method for the study of rapid changes in outflow facility and intraocular pressure are discussed, with a series of definite recommendations. A saline solution for anterior chamber infusion that preserves the outflow resistance of the monkey eye has been described. Data are given showing the degree of uncertainty, cause...

There are no oral drugs for human African trypanosomiasis (HAT, sleeping sickness). A successful oral drug would have the potential to reduce or eliminate the need for patient hospitalization, thus reducing healthcare costs of HAT. The development of oral medications is a key objective of the Consortium for Parasitic Drug Development (CPDD). In this study, we investigated the safety, pharmacoki...

Di Bitetti, M. 2001. Food-associated calls in tufted capuchin monkeys (Cebus apella). Doctoral thesis, State University of New York at Stony Brook, New York. Di Bitetti, M. 2003. Food-associated calls of tufted capuchin monkeys (Cebus apella nigritus) are functionally referential signals. Behaviour 140: 565 –592. Fichtel, C. and Hammerschmidt, K. 2002. Responses of red-fronted lemurs to experim...

OBJECTIVE Vervet monkeys are common in most tree-rich areas of South Africa, but their absence from grassland and semi-desert areas of the country suggest potentially restricted and mosaic local population patterns that may have relevance to local phenotype patterns and selection. A portion of the mitochondrial DNA control region was sequenced to study patterns of genetic differentiation. MET...