Introduction Ultrasound is a non-invasive and bedside accessible method of cardiac function monitoring. Cardiac echocardiography has several limitations due to difficulties to obtain an acceptable acoustic window in critical care settings. Left ventricular outflow tract (LVOT) velocity time integral (VTI) can be measured in most critical care patient and is an useful tool for this purpose. Calc...

Contact address: Zsolt Gyalai, MD Department of Cardiology, Mureş County Clinical Hospital Gheorghe Marinescu Street, no. 1, 540103, Târgu Mureş, Romania E-mail address: [email protected] 1 Department of Cardiology, Mureş County Clinical Hospital, Târgu Mureş, Romania 2 Department of Cardiology, Emergency Institute of Cardiovascular Diseases and Transplantation, Târgu Mureş, Romania 3 Univ...

BACKGROUND Biventricular (Biv) pacemaker echo optimization has been shown to improve cardiac output however is not routinely used due to its complexity. We investigated the role of a simple method involving computerized pre-ejection time (PEP) assessment by radial artery tonometry in guiding Biv pacemaker optimization. METHODS Blinded echo and radial artery tonometry were performed simultaneo...

OBJECTIVES The purpose of this study was to determine if AV delay optimization with continuous-wave Doppler aortic velocity-time integral (VTI) is clinically superior to an empiric program in patients treated with cardiac resynchronization therapy (CRT) for severe heart failure. BACKGROUND The impact of AV delay programming on clinical outcomes associated with CRT is unknown. METHODS A rand...

BACKGROUND Although multiple echocardiographic methods exist to calculate cardiac output (CO), they have not been validated in mice using a reference method. METHODS Echocardiographic and flow probe measurements of CO were obtained in mice before and after albumin infusion and inferior vena cava occlusions. Echocardiography was also performed before and after endotoxin injection. Cardiac outp...

Valence tautomeric interconversion (VTI) is a reversible process occurring in metal complexes in which an intramolecular metal-ligand electron transfer is accompanied by a change of metal ion spin state, creating two switchable electronic states (redox isomers). Herein, we describe the low-temperature, 30-100 K, single-crystal study of the [Co(diox)2(4-CN-py)2]·benzene complex (1) (diox = 3,5-d...

In microgravity (microG) humans have marked changes in body fluids, with a combination of an overall fluid loss and a redistribution of fluids in the cranial direction. We investigated whether interstitial pulmonary edema develops as a result of a headward fluid shift or whether pulmonary tissue fluid volume is reduced as a result of the overall loss of body fluid. We measured pulmonary tissue ...

BACKGROUND The mechanoenergetic effects of atrioventricular delay optimization during biventricular pacing ("cardiac resynchronization therapy", CRT) are unknown. METHODS Eleven patients with heart failure and left bundle branch block (LBBB) underwent invasive measurements of left ventricular (LV) developed pressure, aortic flow velocity-time-integral (VTI) and myocardial oxygen consumption (...