vitamin e is a potent reactive oxygen metabolites (rom) scavenger. it is a lipid-soluble vitamin and its main function is to protect polyunsaturated fatty acids against oxidative stress. twenty-five mechanically ventilated intensive care unit (icu) adult patients participated in a prospective randomized clinical trial receiving either placebo (10 patients) or 3 im doses (1000 iu each) of vitami...

Management of acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) is largely supportive, with the use of mechanical ventilation being a central feature. Recent advances in the understanding of ALI/ARDS and mechanical ventilation have revealed that lung-protective ventilation strategies may attenuate ventilator-associated lung injury and improve patient morbidity/mortality...

This study explores the assumption that 81mKr static images represent regional ventilation. Dynamic acquisition of 81mKr ventilation images permits creation of time-activity curves and the possible separation of the confounding influences of ventilation and volume. By using a two-compartment gas mixing lung phantom, the results demonstrate that both total and tidal 81mKr are closely related to ...

the effect of chair position on respiratory parameters in patients undergoing mechanical ventilation     fallahinia ghh [1] ,baghcheghi n [2] ,oshvandi kh [3] *,taher a [4] , soltanian ar [5]     received: 7 feb, 2013 accepted: 15 may, 2013    abstract  background & aims : there are many barriers to the movement of patients requiring mechanical ventilation and these patients are at risk for com...

OBJECTIVES a) To describe the introduction of noninvasive means to provide positive-pressure ventilation in acute respiratory failure; b) to describe the physiologic response to noninvasive ventilation; c) to review the current published literature on using noninvasive ventilation in patients with acute hypercapnic and/or hypoxemic respiratory failure; d) to describe the technique of applying m...

a bstract             mechanical ventilation is one of the major supportive interventions in intensive care units. weaning the patients from mechanical ventilation and its related criteria are of great importance due to the related complications. as there is no comprehensive standard to allocate the time of weaning and due to lack of local research in this fi eld, development of a comprehensive...

OBJECTIVE To determine the safety, feasibility, and lung-recruitment efficacy of an explicit ventilation protocol combining high-frequency oscillatory ventilation and recruitment maneuvers. DESIGN Prospective, multiple-center, single-intervention pilot study. SETTING Four university-affiliated intensive care units. PATIENTS Twenty-five patients with early acute respiratory distress syndro...

BACKGROUND High-frequency oscillatory ventilation is an alternative ventilation mode that improves oxygenation in trauma patients in whom conventional ventilation strategies have been unsuccessful. OBJECTIVE To evaluate the effect of high-frequency oscillatory ventilation on oxygenation, survival, and parameters predictive of survival in trauma patients. METHODS A retrospective case series ...

BACKGROUND In supine position, pressure support ventilation causes a redistribution of ventilation towards the ventral regions of the lung. Theoretically, a less sensitive support trigger would cause the patient to breathe more actively, potentially attenuating the effect of positive pressure ventilation. OBJECTIVES To quantify the effect of trigger setting, we assessed redistribution of vent...

The sensitivity of tropical cyclone intensity to ventilation of cooler, drier air into the inner core is examined using an axisymmetric tropical cyclone model with parameterized ventilation. Sufficiently strong ventilation induces cooling of the upper-level warm core, a shift in the secondary circulation radially outward, and a decrease in the simulated intensity. Increasing the strength of the...