Background: Pancreatic islet transplantation has emerged as a promising treatment for type I diabetes. However, its efficacy is severely hampered due to poor islet engraftment and revascularization, which have been resulted to partially loss of transplanted islets. It has been shown that local delivery of vascular endothelial growth factor (VEGF) could accelerate transplanted islet revasculari...

Background: Nanotechnology symbolizes a broad discipline with enormous potential in cancer treatment bridging one of the bottlenecks traditional approaches therapy which is an inability to deliver adequate quantities anti-cancer drugs tumor area. Studies on nanoparticles indicate their importance angiogenesis and metastasis. Aim: The present study assessed anti-angiogenesis anti-metastatic effe...

BACKGROUND: Skin wounds are a major challenge, such as full-thickness that need long time to heal. However, the addition of erythropoietin can accelerate wound healing process. AIM: This study was aimed determine effect topical administration on vascular endothelial growth factor (VEGF), epidermal (EGF), and epithelialization in METHODS: randomized controlled trial. Full-thickness were created ...

Introduction: Chorioretinal coloboma (CRC) results from abnormal closure of the embryonic fissure. Choroidal neovascularization (CNV) is a rare complication that associated with choroid. VEGF an important factor in development CNV.
 Case Report: A 52-year-old woman gradual blurred vision left eye since 4 months ago. Right was already she child uncorrected visual acuity (UCVA) 0.5/60. Her r...

Human bone marrow derived mesenchymal stem cells (HBMSCs) have the potential to differentiate into cells such as adipocyte, osteocyte, hepatocyte and endothelial cells. In this study, the differentiation of hBMSCs into endothelial like-cells was induced in presence of vascular endothelial growth factor (VEGF) and insulin-like growth factor (IGF-1). The differentiated endothelial cells were exam...

Among numerical techniques used to facilitate the analysis of biochemical reactions, we can use method moments directly approximate statistics such as mean numbers molecules. The is computationally viable in time and memory, compared solving chemical master equation (CME) which notoriously expensive. In this study, apply a system with constant rate representing vascular endothelial growth facto...

background: oral lichen planus is a chronic inflammatory disease with a poorly understood etiology. the role of angiogenesis in the development of different chronic inflammatory diseases is of great concern. vascular endothelial growth factor (vegf) is an important regulator of angiogenesis. we aimed to evaluate the serum level of vegf in patients with oral lichen planus compared with normal in...

preeclampsia is an important pregnancy disorder with serious maternal and fetal complications which its etiology has not been completely understood yet. early diagnosis and management of disease could reduce its potential side effects. the vascular endothelial growth factor (vegf) family including vegf-a is the most potent endothelial growth factor which induces angiogenesis and endothelial cel...