BACKGROUND Selective serotonin-reuptake inhibitors (SSRIs) are commonly prescribed for the treatment of depression and can be used as nonhormonal alternatives to manage hot flashes for women with a history of breast cancer and unable to take hormone replacement therapy. There are, however, few reports on the efficacy of SSRIs for the treatment of natural postmenopausal climacteric symptoms. In ...

I read, with interest, the original article by AbedzadehKalahroudi et al. about the prevalence and severity of menopausal symptoms and related factors among women aged 40-60 in Kashan (1). In this study, the mean age of menopause was 47.6 ± 4.1 years; the average age is not much different in this study from what is reported for Iranian women (48.2 years) (2). I would like to discuss the risk fa...

BACKGROUND The aim of this study was to investigate clinical efficacy and safety of Remifemin on peri-menopausal symptoms in endometriosis patients with a post-operative GnRH-a therapy. MATERIAL AND METHODS We treated 116 women who had endometriosis with either Remifemin (n=56) 20 mg bid po or Tibolone (n=60) 2.5 mg qd po for 12 weeks after GnRH-a injection. The efficacy was evaluated by Kupp...

The mechanism of action responsible for hypnotherapy's effect in reducing hot flashes is not yet known. The purpose of this study was to examine the role of response expectancies as a potential mediator. Hypnotizability was also tested as an effect moderator. Data were collected from a sample of 172 postmenopausal women, who had been randomized to receive either a 5-week hypnosis intervention o...

BACKGROUND DT56a (Femarelle®) is a natural medication that contains a variety of phytoestrogens derived from tofu. Treatment with DT56a affects bones, vascular tissues and the nervous system in a manner similar to that of estrogen but DT56a acts as an estrogen antagonist in breast and uterine tissues. AIM The objective of this study was to analyze the efficacy of DT56a in the reduction of men...

Due to the limitations of flash memory, such as asymmetric I/O latencies and not-inplace update, two kinds of buffer replacement algorithms exist, namely page-clustered policy and group-clustered policy. The former organizes pages in the page-level, which makes it easy to deal with hot pages, but shows a bad performance when the buffer size is big enough. The latter organizes pages in the group...

OBJECTIVE To determine whether a low dose of P delivered together with E(2) from a vaginal ring on a continuous schedule can prevent endometrial proliferation and yield a bleeding pattern dominated by amenorrhea. DESIGN Longitudinal clinical study. SETTING Three university hospitals. PATIENT(S) Fifty-five women 45 to 75 years of age, not hysterectomized, with E(2) levels of <20 pg/mL and ...

Introduction: The gradual menopausal decline in oestrogens impairs function of the hypothalamic and limbic systems and, therefore, thermoregulation, vasomotor stability, mood regulation and psychological wellbeing. The significantly reduced dopaminergic activity and melatonin secretion increased in hot flushes, psychological symptoms and poor sleep quality. When hormone replacement therapy (HRT...

OBJECTIVE To critically evaluate the effect of red clover on hot flash, endometrial thickness, and hormones status in postmenopausal and peri- and post-menopausal women. MATERIALS AND METHODS MEDLINE (1966 to July 2014), Scopus (1990 to July 2014), and the Cochrane Central Register of Controlled Trials (The Cochrane Library issue 1, 2014) were searched for published randomized controlled Tria...

With the increased sophistication and use of heated gas, fire, and explosion simulations in computer graphics applications, there is a corresponding impetus to improve the visual realism in the rendering of such simulated phenomena. In visualizing these turbulent fluids, an appropriate incorporation of their incandescent properties into the rendering significantly enhances the realism of visual...