Endothelial microparticles (EMP) are complex vesicular structures shed from activated or apoptotic endothelial cells. They play a remarkable role in coagulation, inflammation, endothelial function, and angiogenesis and thus disturb the vascular homeostasis, contributing to the progression of vascular diseases. As a cause or a consequence, elevated levels of EMP were found in plasma from patient...

Background Previously we demonstrated the differentiation pathway of mouse, monkey and human ES cells to vascular cell components [1-3]. In addition, we showed the therapeutic potential of these ES-derived vascular cells. When transplanted in mouse hind-limb ischemia model, these cells were incorporated in host vessels in the ischemic lesion and contributed to host neovascular formations [4]. I...

Background: Endometriosis is known as one of the most common disease in women of reproductive age. Due to importance role of vascular endothelial growth factor (VEGF) in neo-vascularization for the implantation of endometrial cell and different reported results for VEGF level in the serum and peritoneal fluid (PF) in endometriosis patients, this study was designed to determine the serum and PF ...