OBJECTIVE We have previously shown that the tumor necrosis factor receptor 2 (TNFR2) protein is highly upregulated in vascular endothelium in response to ischemia, and a global deletion of TNFR2 in mice blunts ischemia-induced arteriogenesis and angiogenesis. However, the role of endothelial TNFR2 is not defined. In this study, we used endothelial cell (EC)-specific transgenesis of TNFR2 (TNFR2...

Two hundred children who had been injured at school and sought hospital treatment were studied. Younger children tended to be brought to the Accident and Emergency Department later after the injuries than the older children, and one in seven of those under 15 years attended alone or without a legally acceptable guardian. Sixteen per cent of the 204 injuries were fractures, of which 70% were to ...

This article presents a synthesis on aging of the human cerebral cortex, and also a review of the approaches to motor control rehabilitation following a cerebral vascular accident (CVA). Throughout the discussion on the clinical implications, the author advises the rehabilitation professionals to encourage older patients perform their activities of daily living (ADL) using both upper extremitie...

OBJECTIVE To compare axillary brachial plexus block and Bier's block as methods of providing upper limb anaesthesia. METHODS Axillary brachial plexus or Bier's blocks were performed on all patients requiring upper limb anaesthesia in a three month period. For Bier's block, a single cuff tourniquet and 3 mg/kg 0.5% prilocaine were used. For axillary plexus block, 40 ml 1% lignocaine with adren...

spasticity is one of the common complications in upper motor neuron lesions and without appropriate treatment it causes disturbances in movement pattern. assessments of patients are effective in patient`s management. modified ashworth scale (mas) is one of the criteria in qualitative assessment of spasticity, and there are lots of controversies about its validity. the purpose of this study is t...

Acute compartment syndrome (ACS) is an uncommon complication of uncontrolled hypothyroidism. If unrecognized, this can lead to ischemia, necrosis and potential limb loss. A 49-year-old female presented with the sudden onset of bilateral lower and upper extremity swelling and pain. The lower extremity anterior compartments were painful and tense. The extensor surface of the upper extremities exh...

abdominal aortic coarctation is an extremely rare vascular pathology. its etiology can be congenital or acquired. here we present a case of acquired infrarenal abdominal coarctation in a 66-year-old woman who complained of low back and legs pain. she had no signs of resting lower limb ischemia, with diminished distal pulses and normal blood pressure in upper and lower extremities. magnetic reso...

BACKGROUND Acupuncture may improve motor function in patients with chronic hemiparetic stroke, yet the neural mechanisms underlying such an effect are unknown. As part of a sham-controlled, randomized clinical trial testing the efficacy of a 10-week acupuncture protocol in patients with chronic hemiparetic stroke, we examined the relationship between changes in function of the affected upper li...