We have studied the use of intra-vas deferens local anaesthesia in 70 patients undergoing vasectomy as day-case patients. Patients were allocated randomly to either a control or treatment group. In the treatment group, 0.5% bupivacaine 1 ml or 0.9% saline 1 ml was injected into the lumen of the right or left vas deferens in a randomized blinded design. The control group did not receive an injec...

Peptides with opioid activity are found in pepsin hydrolysates of wheat gluten and a-casein. The opioid activity of these peptides was demonstrated by use of the following bioassays: 1) naloxone-reversible inhibition of adenylate cyclase in homogenates of neuroblastoma X-glioma hybrid cells; 2) naloxone-reversible inhibition of electrically stimulated contractions of the mouse vas deferens; 3) ...

This review focuses on the expression and function of muscarinic acetylcholine receptors (mAChRs), alpha1-adrenoceptors and relaxin receptors in the male reproductive tract. The localization and differential expression of mAChR and alpha1-adrenoceptor subtypes in specific compartments of the efferent ductules, epididymis, vas deferens, seminal vesicle and prostate of various species indicate a ...

Objective—The effects of vasectomy on testes and related structures are disputable. The aim of this study was to determine whether the reproductive organs of rabbits were influenced after 12 months vasectomy. Study design—Bilateral vasectomy was performed on 10 male adult New Zealand Big Eared White Rabbits (another 10 rabbits set as sham operated group) and tissue samples were examined by ligh...

Using the technique of homogenization and subsequent density gradient centrifugation combined with ultrastructural analysis, the subcellular localization of noradrenaline and neuropeptide Y (NPY) was studied in vas deferens of castrated male rats. Noradrenaline showed two peaks in the gradient: one major peak at low density and another at high density. Only one NPY peak was seen, which coincide...

The male reproductive system of Graphosoma lineatum (Linnaeus 1758) is studied morphologically and histologically using both light and scanning electron microscopes (SEM). On the basis of histological sections and whole morfological studies, the following elements in the structure of the male reproductive system of G. lineatum have been examined: the structure of a pair of testis containing the...

The natural polyamines spermine and spermidine, and the diamine putrescine, were extracted from rooster testis cells separated by sedimentation at unit gravity, and from vas-deferens spermatozoa. The ratios spermine/DNA and spermidine/DNA were kept relatively constant throughout spermatogenesis, whereas the ratio putrescine/DNA rose in elongated spermatids. The cellular content of spermine, spe...

Vasectomy is the most effective form of male sterilisation and is performed worldwide by urologists, general surgeons and family practitioners [ 1 ] . Various techniques for vasectomy have been described, but the underlying principle is to remove a satisfactory segment of the vas deferens, followed by closure of the proximal and distal ends, to ensure that the patient achieves azoospermia whils...