BACKGROUND The importance of the isatinic quinolyl hydrazones arises from incorporating the quinoline ring with the indole ring in the same compound. Quinoline ring has therapeutic and biological activities. On the other hand, isatin (1H-indole-2,3-dione) and its derivatives exhibit a wide range of biological activities. Also, the indole ring occurs in Jasmine flowers and Orange blossoms. Recen...

The pac1+ gene of the fission yeast Schizosaccharomyces pombe is essential for viability and its overexpression induces sterility and suppresses mutations in the pat1+ and snm1+ genes. The pac1+ gene encodes a protein that is structurally similar to RNase III from Escherichia coli, but its normal function is unknown. We report here the purification and characterization of the Pac1 protein after...

Tight junctions play a key role in restricting or regulating passage of liquids, ions and large solutes through various biological barriers by the paracellular route. Changes in paracellular permeation indicate alteration of the tight junction. However, it is very difficult to obtain the structural change information by measuring paracellular flux based on transepithelial electrical resistance ...

By means of EPR spectroscopy the behaviour of the vanadocene dichloride (I), Cp(2)VCl(2) (Cp=eta(5)-C(5)H(5)), in various deoxygenated and non-deoxygenated physiological media and therapeutic solution as well as in blood plasma and stabilized human blood was studied. On the basis of measured values of isotropic spectroscopic splitting factor g(iso) and isotropic hyperfine coupling constant A(is...

The title oxidovanadium(V) complex, [V(C(17)H(16)N(2)O(3))(CH(3)O)O], was obtained by the reaction of 3-eth-oxy-2-hy-droxy-benzaldehyde, 4-methyl-benzohydrazide and vanadyl sulfate in methanol. The V(V) atom is coordinated by the O,N,O'-tridentate Schiff base ligand, one methano-late O atom and one oxide O atom, forming a distorted VO(4)N square-pyramidal coordination geometry. The oxide O atom...

Introduction 5-Hydroxymethyl-2-furaldehyde (HMF), as diformylfurane precursor (DFF), is obtained from fructose or glucose dehydration. DFF is a versatile chemical, and there are numerous reports describing various applications as a monomer, as starting materials for the synthesis of pharmaceuticals and antifungal agents [1]. To date, few reports describe the use of air to oxidize (HMF) with het...

The title compound, nona-niobium vanadium penta-cosa-oxide, was prepared by a solid-state reaction at 1198 K. It is isotypic with Nb9AsO25, Nb9PO25 and Ta9VO25. The structure consists of NbO6 octa-hedra (one with 4/m.. and two with m.. symmetry) and VO4 tetra-hedra (-4.. symmetry) sharing corners and edges to form a three-dimensional framework. This framework can be considered as a junction bet...