OBJECTIVES The interaction of hydroxyurea (HU) with serum albumins (SAs) has not been investigated so far. However, it necessitates the interaction study of HU with SAs in phosphate buffer of pH 7.4. METHODS The binding of HU on bovine serum albumin (BSA) and human serum albumin (HSA) was studied in vitro under simulated physiological conditions by spectroscopic methods viz., fluorescence, FT...

The photophysical properties of 2-phenyl-naphtho[1,2-d][1,3]oxazole, 2(4-N,N-dimethylaminophenyl)naphtho[1,2-d][1,3]oxazole and 2(4-N,N-diphenylaminophenyl) naphtho[1,2-d][1,3]oxazole were studied in a series of solvents. UV-Vis absorption spectra are insensitive to solvent polarity whereas the fluorescence spectra in the same solvent set show an important solvatochromic effect leading to large...

Three rhodamine derivatives exhibiting electrofluorochromic properties were investigated by cyclic voltammetry and UV-Vis/fluorescence spectroelectrochemistry. Rhodamine 101 (Rh101, compound 1) was used as a reference model. In compound 2, the carboxylate anion of Rh101 was replaced by an alkyne moiety to allow further functionalization. The compound 3 was prepared from 2 by conversion of the a...

A novel asymmetric phenol-based 'end-off' dinucleating ligand 2-{[(2-piperidylmethyl)amino]methyl}-4-bromo-6-[(1-methylhomopiperazine-4-yl)methyl]phenol (HL) and three dinuclear nickel(II) complexes, [Ni₂L(μ-OH)] (ClO₄)₂ (1), [Ni₂L(DNBA)₂(CH₃CN)₂]BPh₄ (2) and [Ni₂L(BPP)₂(CH₃CN)₂]BPh₄ (3) have been synthesized and characterized by a variety of techniques including: NMR, infrared and UV-vis spect...

Abstract Barium titanium borate glasses doped with ytterbium ions were fabricated via standard melt quenching technique. The building structure of the glass matrices ascendant ratios studied using Raman and FTIR spectroscopies. UV–Vis–NIR optical absorption spectra investigated used to calculate bandgaps, Urbach energies, refractive indices, metallization criterion, basicity, dispersion paramet...

A highly selective and sensitive chemodosimeter for detection of cyanide ions in HEPES buffer and in the presence of blood serum using a ratiometric approach through dual UV-Vis and fluorescence channels with the lowest detection limit of 0.08 ppb has been synthesized.

A mononuclear Cr(v)-oxo complex, [CrV(O)(6-COO--tpa)](BF4)2 (1; 6-COO--tpa = N,N-bis(2-pyridylmethyl)-N-(6-carboxylato-2-pyridylmethyl)amine) was prepared through the reaction of a Cr(iii) precursor complex with iodosylbenzene as an oxidant. Characterization of 1 was achieved using ESI-MS spectrometry, electron paramagnetic resonance, UV-vis, and resonance Raman spectroscopies. The reduction po...

Here we present a simple route to produce well-defined photo-reduced silver nanoparticles on TiO2 containing zeolites. We used natural and artificial irradiation sources to study their effect on the particle size distribution. The samples were investigated by electron microscopy, X-ray diffraction, fluorescence microscopy and UV-Vis diffuse reflectance spectroscopy.

We report herein the first small molecule based self-assembled fluorescent trinuclear Zn(II) supramolecular cylindrical motif as a structural and functional model of the active site of P1 nuclease. The DNA binding of the same was investigated through UV-Vis, fluorescence and circular dichroism studies.