Several epidemiological studies have demonstrated the relationship between the existence of fibroids and the occurrence of infertility; indeed fibroids have been reported in 25-30% of infertile women and are responsible for them alone to 2 to 3% of infertility cases when no other cause was found. The objective of this study was to investigate the probable association between the presence of a f...

OBJECTIVES Uterine fibroids are the most common benign tumors in women of reproductive age. Evidence suggest that ovarian steroid hormones, in particular, progesterone play a major role in promoting leiomyoma development and growth. For the last years there was an extensive research on selective progesterone receptor modulators and their use in therapy. Ulipristal acetate (UPA) is one of these ...

Uterine fibroids are the commonest benign tumours of women and affect all races with a cumulative lifetime risk of around 70%. Despite their high prevalence and the heavy economic burden of treatment, fibroids have received remarkably little attention compared to common female malignant tumours. This article reviews recent progress in understanding the biological nature of fibroids, their life ...