The replication proteins Rep and Rep' of porcine circovirus type 1 (PCV1) are both capable of introducing and resealing strand discontinuities at the viral origin of DNA replication in vitro underlying genome amplification by rolling-circle replication. The PCV1 origin of replication encompasses the minimal binding site (MBS) of the Rep and Rep' proteins and an inverted repeat with the potentia...

Background Diabetes Mellitus is a metabolic disorder characterized by insulin resistance with several abnormalities which trigger neuronal complications, neurodegeneration, and cognitive impairments. Repaglinide (REP) an insulinotropic, neuroprotective agent short-action poor absorption characteristics. Hence, the present study was aimed to investigate efficacy of REP-loaded lipid polymer-hybri...

tight and could turn on the tiniest misstep. Rep. Hill has a secret: She has been diagnosed with the early signs of Alzheimer's disease the past summer. Based on her doctor's diagnosis of slow progression that can be treated with experimental drugs, Rep. Hill has decided to stay in the race. Joe Cracker has an agenda: he does not want Rep. Hill elected to the Senate. He is strongly opposed to m...

ninety one monoconidial bipolaris isolates were obtained from lesions on different parts of rice in different locations of mazandaran province during the summer of 2009. bipolaris species were identified using morphological features such as color and shape of colony and color and size of conidia and conidiophores. the isolates were separated into two species; 85 (93.4%) isolates belonged to bip...

in 2011-2012 surveys for phytoplasma diseases, eggplant )solanum melongena l.( plants with phyllody symptoms were observed in eggplant fields of roodan (hormozgan province of iran). agent of roodan eggplant phyllody (rep) was transmitted from phyllody affected eggplant to eggplant and tomato by grafting and to periwinkle via dodder inoculation inducing phytoplasma-type symptoms. phytoplasmal in...

L Abstract—This paper presents an Iterative Learning Controller (ILC) design for Self-Servowriting (SSW) process in Hard Disk Drives (HDDs). In SSW, the position and timing information are written onto the disk surface by referring to the previously written servo information. This process is repeated until the whole disk is completely written. The main issue in this process is Radial Error Prop...

The authors are investigating reverse engineering for reconstructing the shape of simple mechanical parts. Currently, preliminary B-rep models can be created by fitting surfaces to point clouds obtained by scanning an actual part using a 3D laser scanner. The resulting model, although valid, is often not suitable for purposes such as redesign. This is because expected regularities and constrain...

The position of the inflexion point in the red edge (680 nm to 780 nm), termed the red-edge position (REP) has been used as a measure to estimate foliar chlorophyll or nitrogen content. In this study, we assessed the utility of a new technique for extracting the REP, the linear extrapolation method recently proposed by Cho and Skidmore [Remote Sens. Environ. (in press)]. The assessment was base...

The conformational states of Escherichia coli Rep helicase undergoing ATP hydrolysis while bound to a partial-duplex DNA (pdDNA) were studied using single-molecule FRET. Crystallographic studies showed that Rep bound to single-stranded DNA can exist in open and closed conformations that differ in the orientation of the 2B subdomain. FRET measurements between eight Rep mutants donor-labeled at d...