background and objectives: biological scaffold resources composed of extracellular matrix (ecm) have been shown to make easy the practical remodeling of various tissues in both animal and human studies. the goal of current study was to make sheet form of ecm from sheep’s urinary bladder. methods: ecm was extracted from sheep’s urinary bladder according to standard method. scanning electron mic...

A 63-year-old Japanese man complained of hematuria and pollakisuria for several months. Computed tomography and cystography disclosed an infiltrative tumor mass in the irregularly thickened apical and posterior walls of the urinary bladder. Narrowing of the vesical lumen and posterior extension of the tumor into the pelvic cavity were also noted. After palliative ureterocutaneostomy, 60 Gy irra...

In article number 20220078, Ying Tan and co-workers describe a convenient visualized automatic gold nanoparticles (AuNPs) counting strategy based on dark-field microscopy (DFM) for single-cell level telomerase activity detection. this cover, after magnetic separation DNA double-strand unwinding, AuNPs were collected, the was quantitatively measured by visually bright spots DFM. This can clearly...

Multiple studies in the general population have suggested that subjects with the glutathione S-transferase M1 (GSTM1)-null genotype, who lack functional GSTM1, are at higher risk for bladder cancer. To evaluate the impact of the GSTM1-null genotype on bladder cancer caused by occupational exposure to benzidine and to determine its influence on benzidine metabolism, we carried out three compleme...

• Offer a urine dipstick test to detect blood, glucose, protein, leucocytes, and nitrites. • Offer the patient information and advice, and give him the time to decide whether he wishes to have prostate specific antigen testing if: -His symptoms suggest bladder outlet obstruction secondary to benign prostatic enlargement or -His prostate feels abnormal on digital rectal examination or -He is con...

Cancer stem cells (CSCs), which have the abilities of tumor-initiating, self-renewal and differentiation, are thought to cause post-therapeutic recurrence and the progression of cancer. However, CSCs are commonly resistant to current cancer therapies including chemotherapy and radiotherapy. In this study, we isolated cancer stem celllike side population (SP) cells from human bladder cancer cell...

  Background and Objectives: Biological scaffold resources composed of extracellular matrix (ECM) have been shown to make easy the practical remodeling of various tissues in both animal and human studies. The goal of current study was to make sheet form of ECM from sheep’s urinary bladder. Methods: ECM was extracted from Sheep’s urinary bladder according to standard method. Scanning electron ...

Bladder cancer is one of the most common tumors of the genitourinary tract. Here, we use phage display to identify a peptide that targets bladder tumor cells. A phage library containing random peptides was screened for binding to cells from human bladder tumor xenografts. Phage clones were further selected for binding to a bladder tumor cell line in culture. Six clones displaying the consensus ...

Tumour-associated antigens detected in cells obtained from bladder washings or tumours are useful markers in bladder cancer. Flow cytometry is commonly used to quantify immuno-stained cells. A straightforward way to analyze data is to count the fluorescent cells above a threshold empirically determined on a control histogram representation. However, specific antigens expressed at highly variabl...

Bladder cancer is the fourth most common malignancy in American men and almost 25% is muscle invasive at the time of diagnosis (Cancer Facts and Figures, 2009; Nieder et al., 2008). Currently, most effective local treatment of muscle invasive bladder cancer and noninvasive, high-grade bladder tumors that recur or progress despite intravesical therapies is open radical cystoprostatectomy with ur...