Methods MRI was performed in 40 patients (27 males, age 62±9 years) who were scheduled for pulmonary vein isolation (PVI) and had a glomerularfiltration rate (GFR) of >30ml/min. A total of three MRIs were acquired prior to, directly after and 24 hours after PVI, using weightdependent dosages of gadolinium pententat (Gd-DPTA). 46,8±14,9 ml Gd-DPTA was given within a 3±1 day period. Renal functio...

Purpose: To investigate the mechanism of resveratrol protection against sepsis-induced acute kidney injury in mice.
 Methods: A model was established mice by cecal ligation and puncture (CLP). Sixty healthy male ICR were randomly divided into sham operation (sham) group, (CLP) CLP + low-dose (20 mg/kg) treatment (CLP ResL) high-dose (40 ResH) group Klotho (0.01 Klotho) group. All administe...

Introduction: The effect of fluid and food restrictions on biochemical substances relating to the renal and bone function of pregnant women is not well defined. The purpose of this study is to evaluate the effects of fluid and food restriction on the following substances in pregnant fasting women during Ramadan: blood urea nitrogen (BUN), creatinine (Cr), calcium (Ca), phosphorus (P), and alkal...

BACKGROUND Endothelin-1 (ET-1) is a vasoconstrictor peptide that mediates cell proliferation, fibrosis, and inflammation. ET-1 has 2 receptors A and B. OBJECTIVES The present study investigated whether administration of ET-1 receptor type A antagonist leads to protect cisplatin (CP) induced nephrotoxicity in ovariectomized-estradiol (Es) treated rats. MATERIALS AND METHODS Thirty-six ovarie...

Objective This meta-analysis aims to compare the efficacy and safety of peritoneal dialysis (PD) hemodialysis (HD) in treatment diabetic kidney failure. Methods Five databases were selected retrieve research on PD HD for failure until 6 August 2022. A fixed-effects or random-effects model was utilized calculate standardized mean difference (SMD) odds ratio (OR) based heterogeneity among studies...

The aim of this study was to determine the effect of different physical forms and urea treatment of rice straw on feed intake, rumen fermentation, and milk production. Four, multiparous Holstein crossbred dairy cows in mid-lactation with initial body weight (BW) of 409±20 kg were randomly assigned according to a 4×4 Latin square design to receive four dietary treatments. The dietary treatments ...

objective: this study defines the relationship between salivary beta-2 microglobulin (ß2-m) and intensity of uremia in male patients diagnosed with chronic renal failure (crf). materials and methods: in total of 42 males were enrolled in a case-control study. there were 21 cases of crf and 21 control cases. we collected 10cc of saliva plus 5 cc of blood from all patients to determine ß2-m, bloo...

OBJECTIVE We aimed to determine if abnormal laboratory values which may indicate volume depletion are associated with increased odds of experiencing a hospital-acquired fall. DESIGN Matched case-control study. SETTING Four hospitals located in the Southeast USA. PARTICIPANTS Data from 699 adult fallers and 1189 matched controls (non-fallers) were collected via chart review from 2005 to 20...

BACKGROUND Simvastatin is a widely used medication in cardiac care. Here we evaluate the role of ATP sensitive potassium (KATP) channels in simvastatin induced renal protection after renal ischemia/reperfusion (I/R) injury. METHODS A total of 81 male Wistar rats, were treated with simvastatin (10 and 20mg/kg/day; gavage, one week). Some groups received glibenclamide (KATP channel inhibitor; 5...

BACKGROUND Creatine monohydrate has become a very popular nutritional supplement for its ergogenic effects. The safety of creatine monohydrate has previously been confirmed. However with each novel form of creatine that emerges, its safety must be verified. Therefore, the purpose of this study was to examine the safety of a novel form of creatine, creatine nitrate (CN), over a 28 day period. ...