As part of the Phase III luminosity upgrade, the Cornell Electron-Positron Storage Ring (CESR) RF system has been upgraded from normal conducting (NRF) to superconducting (SRF) cavaties. The new superconducting cavities change the overall impedance of CESR and thus change the longitudinal bunch distribution. Measurements of the single bunch longitudinal distribution have been made using a strea...

Abstract Forkhead transcription factor (FoxO) plays key roles in the induction of various downstream genes involved inhibition cellular metabolism, cell death, cycle, and oxidative stress responses. FoxO6 is expressed liver, skeletal muscle, hippocampus brain. also has been proposed to play a role promotion insulin resistance, inflammation. In this study, we tried determine neuroinflammation in...

Objective(s): Aspiration is a common cause of acute lung injury (ALI), which lacks an effective treatment. Inflammation and oxidative stress play key roles in ALI development. Silymarin is an active extract of Silybum marianum plant seeds (milk thistle). Silymarin has potent anti-inflammatory and antioxidant effects; however its role in aspiration induced ALI has not b...

This paper makes the detailed analyses of computational complexities and related parameters selection on our proposed constrained learning neural network root-finders including the original feedforward neural network root-finder (FNN-RF) and the recursive partitioning feedforward neural network root-finder (RP-FNN-RF). Specifically, we investigate the case study of the CLA used in neural root-f...

In this study, NRTL and UNIQUAC thermodynamic models were used to predict the composition of ternary mixtures of solvents+ m/o/p-cresol+ water in organic and aqueous phases. Various solvents are used for the separation of cresols from water. In this study, methyl propyl ketone, methyl isopropyl ketone, methyl butyl ketone, and methyl isobutyl ketone solvents were investigated. Intermolecular in...

Abstract The ongoing pandemic of COVID-19, caused by SARS-CoV-2 infection, has threatened the global health. Since first case infection was reported in December 2019, rapidly spread all over world and millions deaths. As vaccination is best way to protect host from invading pathogens, several vaccines have been developed prevent saved huge numbers lives so far. However, constantly change their ...

Abstract Accumulating data have highlighted the role of monocytes/macrophages in immune escape by generating immunologically “cold” tumors that do not respond to immunotherapy. CD244 (SLAMF4, 2B4), a member signaling lymphocyte activation molecule family, is expressed on myeloid cells, but its precise has been elucidated. Using monocyte lineage-specific CD244-deficient micechallenged with B16F1...

Cystic fibrosis is characterized by recurring pulmonary exacerbations that lead to the deterioration of lung function and eventual lung failure. Excessive inflammatory responses by airway epithelia have been linked to the overproduction of the inflammatory cytokine IL-6 and IL-8. The mechanism by which this occurs is not fully understood, but normal IL-1beta mediated activation of the productio...

We studied the implication of focal adhesion kinase (FAK) in cardiac mitochondrial biogenesis induced by mechanical stress. Prolonged stretching (2-12 h) of neonatal rat ventricular myocytes (NRVM) upregulated the main components of mitochondrial transcription cascade [peroxisome proliferator-activated receptor coactivator-1 (PGC-1α), nuclear respiratory factor (NRF-1), and mitochondrial transc...