ÐEstrogens can in ̄uence the survival, plasticity and function of many adult neurons. Many of these effects, such as neurite outgrowth and increased dendritic spine density, are mediated by changes in neuronal cytoskeletal architecture. Since neuro®lament proteins play a key role in the maintenance and remodeling of the neuronal cytoskeleton, we postulated that changes in neuro®lament light chai...

BACKGROUND Estradiol is known to inhibit food intake (FI), water intake (WI) and body weight (BW) across the species including women and it is most evident in rats. Ovariectomy in rats and menopause in women produce hyperphagia and obesity. Estradiol substitution in ovariectomized (OVX) rats and hormone replacement in women reverses these changes suggesting that lack of estradiol causes eating ...

OBJECTIVE The purpose of this study was to evaluate the different patterns of bone loss between the lumbar spine and the femur after ovariectomy in rats. METHODS Twenty-four female Sprague-Dawley rats underwent a sham operation (the sham group) or bilateral ovariectomy (the ovariectomized group). Four and eight weeks after operation, six rats from each of the two groups were euthanized. Serum...

background: learning and memory are the most intensively studied subjects in neuroscience. two sites of mammalian brain which are important in learning and memory are ca1 region of hippocampus and purkinje cell layer of cerebellum. so, the aim of present investigation was to study of the effect of ovariectomy and passive avoidance learning on nr1 subunit of n-methyl-d-aspartate (nmda) receptor ...

Ovariectomy in Queens: Two portals Laparoscopy vs Conventional Approach Navid Salmanzadeh Zahedani1 , Jalal Bakhtiari1, DVM, PhD, Alizera Khalaj2, MD, Behnam Vafadari1 , D. V. M., Amir Niasari-Naslaji3, DVM, PhD Objective- The purpose of this study was to compare two portal laparoscopy and conventional approach for ovariectomy in queen. Design- Retrospective study. Animals- Adult healthy ...

In this study, the effects of Urtica dioica hydro-alcoholic extract were investigated on the blood glucose and lipid profiles of female ovariectomized and non-ovariectomized rats. In total, 32 adult female rats were divided into four groups (eight each) including control and ovariectomy groups as well as non-ovariectomy and ovariectomy groups treated with 200 mg kg-1 of ...

Background and objectives: Increased oxidative stress and altered antioxidant levels play an essential role in the pathogenesis of diabetes mellitus. Menopause is associated with increased food intake, weight gain, metabolic disorders, and increased level of inflammatory and oxidative stress factors. This study evaluated effects of oleuropein extract on brain tissue and serum oxidative status i...