Techniques that allow the selective stimulation of the erythropoietin-responsive cell population in mice with suppressed multipotential hemopoietic stem cells were used to identify (1) the in vivo target cell transformed by Friend virus (FV) into a tumor colony-forming unit and (2) a target cell for FV replication in vivo. Plethoric mice with busulphan-induced reductions in stem cell population...

−− It’s a fact that functional verification (FV) is paramount within the hardware’s design cycle. With so many new techniques available today to help with FV, which techniques should we really use? The answer is not straightforward and is often confusing and costly. The tools and techniques to be used in a project have to be decided upon early in the design cycle to get the best value for these...

Definition 1.1. Formally, a protocol P is a rooted binary tree with each internal node v labelled by either “A” or “B” and two out-edges, one labelled 0 and the other labelled 1. Each leaf has an output label (typically in {0, 1}. There is a function fv associated with node v; if v is labelled A then fv : X → {0, 1} and if v is labelled B then fv : Y → {0, 1}. The bit sent at node v is sent by ...

Factor V (FV) Leiden is the most common genetic defect found in persons of European descent with venous thromboembolism.1 The 1691G.A transition determines the R506Q substitution.2 This suppresses a cleavage site for activated protein C (APC) on FVa, resulting in resistance to APC in a functional coagulation-based assay.3 FV Leiden accounts for over 90% cases of APC resistance, but this phenome...

Introducción: la deficiencia congénita del factor V (FVD) es un trastorno hemorrágico raro causado por mutaciones en el gen FV que reduce cuantitativamente los niveles plasmáticos de FV, cuya incidencia estimada 1 1.000.000 población general y se hereda con patrón autosómico recesivo. La enfermedad clínicamente heterogénea; las complicaciones potencialmente mortales como hemorragias sistema ner...

This paper is devoted to the presentation and analysis of some linear and quadratic finite volume (FV) schemes for elliptic problems with singular solutions due to the non-smoothness of the domain. Our FV schemes are constructed over specially-designed graded triangular meshes. We provide sharp parameter selection criteria for the graded mesh, such that both the linear and quadratic FV schemes ...

Let Fv and Fe be sets of faulty vertices and faulty edges, respectively, in the folded hypercube FQn so that |Fv| + |Fe| ≤ n − 2, for n ≥ 2. Choose any fault-free edge e. If n ≥ 3 then there is a fault-free cycle of length l in FQn containing e, for every even l ranging from 4 to 2 − 2|Fv |; if n ≥ 2 is even then there is a fault-free cycle of length l in FQn containing e, for every odd l rangi...

To investigate the molecular mechanisms of the quantitative factor V (FV) deficiency associated with the FV R2 haplotype, 4 missense mutations, Met385Thr, His1299Arg, Met1736Val, and Asp2194Gly, identified in the R2 haplotype allele, were analyzed by in vitro expression studies. The FV variant carrying all 4 mutations showed a markedly lower steady-state expression level than wild-type FV becau...

En esta investigación se evaluo el efecto de la combinación fibra vidrio y aditivo sikacem PE, cuya procedencia son las botellas que obtuvo en almacenes marca, los cuales van a ser incorporados mezcla del concreto con objetivo alterar su resistencia compresión flexión como objetivos primer nivel segundo nivel, es verificar trabajabilidad asentamiento concreto. La dosificación fue reemplazada re...

Background and Aims: Congenital factor V (FV) deficiency is a rare bleeding disorder with 1 in 1000000 persons in the general population. Individuals with FV activity <1% and very low FV antigen levels are characterized as severe FV deficient patients. Little data is available about the molecular basis of this bleeding disorder in Iran. Materials and Methods: We analyzed 7 unrelated Iranian FV...