The discovery of antimalarial properties ni Plasmochin and acridine derivatives such -is '?tebrin is undoubtedly a great advance in the herapy of malaria. The untoward symptoms which are occasionally observed, their inability to prevent relapses in a certain percentage of cases and their not having a true prophylactic a?tion, inasmuch as they have no action on the ?P?rozoites injected by the mo...

Besides the obvious importance of PIMs and PSMs in MDA, model transformations are undoubtedly the key technology in the realization of the MDA vision [1]. Among other usages, model transformations are the ones responsible for refining PIMs into PSMs (or abstracting away from PSMs to PIMs) and mapping PSMs to concrete middlewarebased implementations, providing thus an elegant approach to adapt P...

Museum Victoria has a significant collection of objects that could be described as ‘computing curiosities’. Undoubtedly, its most important exhibit is CSIRAC (formerly CSIR Mk1), which was the world’s fourth electronic digital computer and the only remaining intact first generation computer in the world. The collection of computers and related items, including calculators, range in date from be...

In recent years, atherosclerosis has come to be recognized as active and inflammatory, rather than simply a passive process of lipid infiltration.1 Inflammation occurs in response to vascular oxidative stress and injury through known and unknown stimuli. Inflammatory triggers undoubtedly include oxidized and glycosylated products (eg, modified lipoproteins). Given their association with inflamm...

Subtyping is undoubtedly useful for the support of incremental reenement and reuse of software components , a crucial feature of object-oriented languages. Types and subtyping for concurrent languages are not yet explored suuciently and tend to be less exible than desired. We propose a principle of dealing with very exible types in concurrent languages. The corresponding type model ensures that...

Across the time, the organizations have improved according to new technologies, therefore it’s been necessary to invest large amounts of money in the acquisition of computer products, undoubtedly this has brought along many advantages, however, not like it would be expected, because in the majority of these organizations it’s been automatized an amount of ordinary tasks in isolated ways, in oth...

The final cleavage event that terminates cell division, abscission of the small, dense intercellular bridge, has been particularly challenging to resolve. Here, we describe imaging innovations that helped answer long-standing questions about the mechanism of abscission. We further explain how computational modeling of high-resolution data was employed to test hypotheses and generate additional ...

Submit Manuscript | http://medcraveonline.com dynamic and systematic procedure intended to achieve the goals of optimum critical care management. In this regard, nurse anesthetists and intensive care nursing personnel are indispensable. Their dedicated efforts guided by the intensivists are undoubtedly responsible for improved patient outcomes. This article is primarily intended for them and ot...

This paper focuses on enhancing the effectiveness of filter feature selection models from two aspects. One is to modify feature searching engines based on optimization theory, and the other is to improve the regularization capability using point injection techniques. The second topic is undoubtedly important in the situations where overfitting is likely to be met, for example, the ones with onl...

Growing evidence indicates parasite inclusion in food-web analyses is a logical default. Comparisons of food webs including and excluding host-parasite interactions demonstrate the influence of parasites on community dynamics. Although including parasites is undoubtedly informative, the necessary level of detail exists for only a handful of systems. In a recent Ecology Letters article, Lafferty...