OBJECTIVE This study evaluated retroperitoneal hematomas produced by bilateral injury of iliac arteries (uncontrolled hemorrhage), blood volume loss, transcapillary refill, the effects of volume replacement on retroperitoneal bleeding and the hemodynamic changes with and without treatment. METHODS Initial blood volume was determined with Tc(99m)-labelled red cells, and bleeding was evaluated ...

INTRODUCTION Lyophilization may facilitate production of a safe, portable, easily storable, and transportable source of platelets for bleeding patients. The objective of this study was to examine the impact of lyophilized human and porcine platelets in a swine liver injury model of nonsurgical hemorrhage. METHODS Anesthetized pigs (40 kg) had a controlled 35% total blood volume bleed from the...

BACKGROUND Reports of survival benefits of early transfusion of plasma with red blood cells (1:1 ratio) in trauma patients suggest that plasma may be a better fluid to replace Hextend for battlefield resuscitation. We studied possible advantages of prehospital resuscitation with plasma compared with Hextend or albumin in a model of uncontrolled hemorrhage. METHODS Male New Zealand white rabbi...

Objective: Experimental animal liver transplantation is the initial step, before application of procedure on humans. Canine and swine were used to perfect technical aspects procedure. Small animals such as rats mainly utilized study metabolic immunological transplantation. In this paper, we describe our experience with attempting in a sheep model. Material method: The model for both donor recip...

AIM Hemophilia A is a rare inherited bleeding disorder resulting from factor VIII deficiency and is a group of diseases characterized by intra-articular and intramuscular bleeding. In this study, we aimed to retrospectively evaluate the treatment outcomes, demographic and clinical characteristics of our patients who were treated and followed up for last 17 years in our pediatric hematology unit...

Abstract Background Uncontrolled bleeding is one of the primary reasons for preventable death in both civilian trauma and military battle field. This study evaluates vitro vivo hemostatic potential four biopolymeric natural gums, namely, gum tragacanth, guar gum, xanthan acacia. In evaluation whole blood clotting time erythrocyte agglutination assay were carried out. cytotoxicity studies with r...

Background/Aims: Transcatheter arterial embolization (TAE) is useful for management of uncontrolled upper gastrointestinal (UGI) bleeding. We investigated clinical outcomes TAE non-variceal bleeding from benign UGI diseases with endoscopic intervention.Methods: This retrospective study performed between 2017 and 2021 across four South Korean hospitals. Ninety-two patients (72 men, 20 women) who...