Human umbilical arteries are unique vessels in that they close quickly and completely at birth. It has been suggested that cyclic uanosine 3',5'-monophosphate (cAMP) in relaxation. This hypothesis has been evaluated in term gestational human umbilical artery segments incubated at 37 degrees C and in room air. (a) The basal cGMP content (1 pmol/mg protein) of artery segments incubated in room ai...

Umbilical and Para umbilical hernia are frequently encountered in surgical practice & account for 10-12% of abdominal wall hernias. 1 Obesity & multiparity are the most important pre disposing factors. 1,12 It has known to occur since biblical times. Umbilical hernia repair has been reported by Celeus in the 1 st century, William Cheselden in 1740. William Mayo’s in 1901 described the classical...

Spontaneous umbilical endometriosis, also known as Villar's nodule, is an unusual location of the endometrial tissue.Whilst in the case of umbilical locations secondary to surgical procedures endometriosis occurs quite frequently,the frequency of the primary umbilical location is lower than 1% of all endometriosis locations. The authors present such a case diagnosed in a young, nulliparous pati...

Primary umbilical endometriosis is a rare disorder and is defined as the presence of ectopic endometrial tissue within the umbilicus. A patient with painful mass in the umbilicus during menstrual period is studied in this paper. The possibility of subcutaneous endometriosis should be considered when an umbilical mass is detected despite the absence of previous surgery. In this case, urachal can...

A method of estimating the magnitude and distribution of umbilical blood flow by means of radioactive microspheres in sheep fetuses in utero is described. Simultaneous measurements of total umbilical flow by this method and the steady-state diffusion technique showed agreement within ± 11%. In 11 fetuses of 90 to 150 days gestational age, the distribution of umbilical flow to the intercotyledon...

Umbilical endometrioma is a rare condition, with an estimated incidence of 0.5%-1% in all patients with endometrial ectopia. Spontaneous abdominal wall endometriosis is an even rarer and more unusual condition with unclear pathogenetic mechanisms. A 44-year-old parous woman presented with an umbilical skin lesion, and no history of bleeding from the umbilical mass or swelling in the umbilical a...

stem cell based treatments are being increasingly explored for their possible potential to treat various cancers. mesenchymal stem cells believed to possess anti-tumor potential and are preferred for their properties like immune privileged nature, ability to migrate to the site of tumor and capability for multilineage differentiation. this tumor tropism property of mscs could be utilized to del...

Abstract Aims The aim of this study was to determine whether a trans-umbilical or peri-umbilical incision is better route for the initial umbilical trocar in general laparoscopic surgery terms post-operative pain, risk surgical site infection (SSI), complications and scar cosmesis. Methods This prospective 128 patients who underwent 97 had during between January 2020 July 2021. Demographic data...

Endometriosis externa is presence of endometrial glands and stroma outside uterus. Umbilical endometriosis (also called Villar’s nodules) subcutaneous are rare conditions that occur in elderly women without any menstrual complaints pelvic endometriosis. The overall incidence umbilical very low (0.1-0.5%). Here we report a case with menstruation woman previous history cesarean section myomectomy...

INTRODUCTION Endometriosis is a common gynecological condition and presents mainly with involvement of the pelvic organs. Extrapelvic presentations in almost all parts of the body have been reported in the literature. However, umbilical endometriosis that is spontaneous or secondary to surgery is uncommon and accounts for only 0.5% to 1% of all endometriosis cases. CASE PRESENTATION A 35-year...