نتایج جستجو برای: ultra low dose of morphine

تعداد نتایج: 21271499  

Hassan Ghoshooni, Hedayat Sahraei, Jamal Shams, Maryam Khosravi, Mina Ranjbaran, Seyedeh Maedeh Fatemi, Shohreh Javadzadeh,

Introduction: Topiramate is an anti-convulsant drug, which produces its effects via glutamate metabotropic receptors inhibition and/or GABA receptor excitation. In the present study, attempts were made to investigate the effects of topiramate on the tolerance to morphine-induced analgesia activity in male NMRI mice (20-30 g). Methods: Hot plate method was chosen for the study. First of all t...

Journal: :General physiology and biophysics 2017
Ercan Ozdemir Ayse Demirkazik Sinan Gursoy Ahmet S Taskıran Olca Kilinc Gokhan Arslan

Several studies have demonstrated that the electromagnetic fields produce analgesic activity. The aim of this study was to investigate the effects of extremely low frequency (ELF) electromagnetic fields (EMF) on morphine analgesia and tolerance in rats. In the study, 78 adult male Wistar albino rats (approximately 240 ± 12 g) were used. The application of 50 Hz magnetic field, each day the same...

A Rezayof M Nasehi MR Zarrindast P Rostami

In the present study, the effects of intra-cerebral hippocampus (CA1) injections of apomorphine D1, D2-like receptors agonists on morphine-induced place preference in male Wistar rats have been investigated. Subcutaneous administration of different dose of morphine sulphate (1, 3, 6 and 9 mg/kg) produced a dose-dependent conditioned place preference (CPP). Intra-cerebral hippocampus (CA1) admin...

A Khatibi , A Haghparast , E Dianati , J Shams , J Zarringhalam ,

Background: Cuminum cyminum fruit essential oil (FEO) dose-dependently can attenuate the expression of morphine tolerance and dependence in morphine-dependent mice. Objective: In this study, the effects of Cuminum cyminum FEO on acquisition and expression of morphine-induced conditioned place preference (CPP) in morphine-sensitized mice were studied. Methods: Repeated subcutaneous (s.c.) adm...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شیراز - دانشکده علوم پایه 1391

a simple, rapid and low-cost scanner spectroscopy method for the glucose determination by utilizing glucose oxidase and cdte/tga quantum dots as chromoionophore has been described. the detection was based on the combination of the glucose enzymatic reaction and the quenching effect of h2o2 on the cdte quantum dots (qds) photoluminescence.in this study glucose was determined by utilizing glucose...

2015
Tohid Seif-Barghi Navid Moghadam Farzad Kobarfard

INTRODUCTION Consumption of codeine can lead to positive urine test for morphine in athletes. Morphine is classified as a prohibited doping drug while Codeine is not. Morphine/codeine ratio is used in forensic medicine to distinguish the consumption of codeine from abuse of morphine and other narcotics. CASE PRESENTATION We present an athlete with positive urine test for morphine with a histo...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تبریز 1390

building on previous studies on the effectiveness of different types of written corrective feedback, the present study aimed at investigating whether direct focused corrective feedback and direct unfocused corrective feedback produced any differential effects on the accurate use of english articles by efl learners across two different proficiency levels (low and high). in current study, the par...

Journal: :journal of paramedical sciences 0
reza movasaghi imam reza teaching hospital, tabriz university of medical sciences, tabriz firooz salehpour imam reza teaching hospital, tabriz university of medical sciences, tabriz ali ahmadvand imam reza teaching hospital, tabriz university of medical sciences, tabriz davood agha-mohammadi imam reza teaching hospital, tabriz university of medical sciences, tabriz abbas ali dorosty imam reza teaching hospital, tabriz university of medical sciences, tabriz reza vafaee proteomics research center, shahid beheshti university of medical sciences, tehran

opiates such as morphine are one of the most effective classes of medication prescribed to treat both acute and chronic pain.they act to suppress pain through mu-receptor activation on primary afferent nerve fibers, dorsal horn neurons and supraspinal pain center neorons. when morphine is administered epidurally, it diffuses to the cord substance, producing analgesia [1],the aim of this study w...

Journal: :The Journal of pharmacology and experimental therapeutics 1997
C A Paronis J H Woods

The antinociceptive and ventilatory effects of morphine and other opioid agonists were determined in three rhesus monkeys during a period of morphine maintenance, as well as before and after the chronic exposure to morphine. Before the onset of the daily dosing regimen, morphine increased tail-withdrawal latencies from 50 degrees C water, with an ED50 of 6.4 +/- 2.1 mg/kg. Daily injection of 3....

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